October 1st 2024
Your daily dose of the clinical news you may have missed.
September 18th 2024
EASD 2024: Amycretin was also found to be safe and well tolerated in adults with obesity and without diabetes.
September 16th 2024
September 11th 2024
EASD 2024: New data shows survodutide may be beneficial for persons with obesity and MASH.
September 3rd 2024
Eli Lilly Open Letter Warns Against Use of Tirzepatide for "Cosmetic Weight Loss"
In an open letter to the public, Lilly decries use of tirzepatide products Mounjaro and Zepbound for nonmedical purposes and warns of counterfeit formulations.
Daily Dose: Tirzepatide Discontinuation Results in Weight Regain
Obesity Medicine Certificates Increase 40% from 2022 to 2023, says ABOM
The American Board of Obesity Medicine says annual first-time certificates now exceed those for cardiology, pulmonology, and medical oncology.
Tirzepatide Demonstrates Sustained Weight Loss but Discontinuation Results in Weight Regain: SURMOUNT-4 Trial
Study participants randomized to placebo for 1 year after 36 weeks on tirzepatide had mean weight regain of 14% vs augmented loss among those who continued on the medication.
Obesity: How Can America Afford to Treat the Disease?
While incretin-based antiobesity medications are the optimal treatment for some, there are other less costly approaches that can support weight loss success, this author says.
Tirzpatide for Chronic Weight Management Now Available in US Pharmacies, Lilly Announces
The dual GIP/GLP-1 mimetic is available by prescription for adults with obesity or overweight with comorbidities and Lilly is offering a savings card program.
Obesity Advocacy Groups Say Exclusion of People with Obesity from Drug Research Must Stop
The 5 leading advocacy groups said the safety of people with obesity is at risk and called on the FDA to change clinical trial inclusion requirements and expedite labeling changes.
Use Weight-First Approach to Educate Patients about Obesity’s Role in HTN
An obesity specialist discusses the importance of using a weight-first approach when educating patients about obesity's role in the development and worsening of hypertension.
Obesity in America: Highs and Lows by State
From highest percentage of children with obesity to lowest percentage of adults with hypercholesterolemia, see how obesity hits home in our new slideshow.
Tirzepatide Approved by FDA for Chronic Weight Management in Adults
The second GLP-1 mimetic-based drug approved for chronic weight management, tirzepatide may outperform semaglutide, the first.
Daily Dose: Tirzepatide Preferred GLP-1 Agonist for Inducing Weight Loss
Tirzepatide Ups Mean Weight Loss by 21% Following Intensive Lifestyle Intervention: SURMOUNT-3
Tirzepatide could help individuals who lose weight with lifestyle change to maintain and augment that loss, a well known challenge among persons with obesity.
Daily Dose: Obesity Before and During Pregnancy Predicts Future CV Health
Tirzepatide Ranked Most Effective GLP-1 Mimetic for Obesity Management in New Meta-Analysis
The 2 highest doses of tirzepatide were ranked most likely to be effective for weight management in persons without diabetes, followed by semaglutide 2.4 mg.
Obesity Before, During Pregnancy Key to Future Cardiovascular Risk, New Research Suggests
A novel study strongly suggests that pre-pregnancy obesity rather than associated adverse pregnancy outcomes is the "culprit" in postpartum heart disease.
GLP-1 Mimetic Semaglutide Is Effective Across Ejection Fraction in Patients with HFpEF and Obesity: New STEP-HFpEF Analysis
Semaglutide treatment reduced weight and was associated with greater, more consistent improvements in HFpEF than other recently studied drug classes.
Daily Dose: Waist-to-Hip Ratio Better Predictor for Mortality than BMI?
FDA Adds New Warnings to Labeling for Ozempic
The addition of ileus as a potential adverse event associated with the GLP-1 mimetic is not the first required for the class by the regulator.
Obesity Expert to Primary Care Clinicians: Keep Learning and Know When to Prescribe Antiobesity Drugs
Sandra Christensen, MSN, ARNP, gives her top strategies on patient selection for treatment with antiobesity medications and how to choose the right drugs for patients.
Daily Dose: Early Childhood Obesity Treatment Found Effective Long-Term
Waist-to-Hip Ratio More Consistently Associated with Mortality vs BMI: New Research
Waist-to-hip ratio was more powerfully and consistently associated with risk of all-cause mortality than BMI or FMI, but can it replace BMI as a clinical indicator?
Abbott, WeightWatchers Announce App Integrating FreeStyle Libre 2 CGM Data
The new app is designed to help persons with diabetes understand how food and activity impact blood glucose levels and to revise behavior accordingly.
Early Initiation of Childhood Obesity Treatment Linked to Better Weight Outcomes Over Time
An intensive parent-support early childhood obesity intervention program led to better weight status outcomes in the long-term compared to standard therapy, report study authors.
Antiobesity Medications: Expert Compares Benefits, Drawback Among Classes
Obesity specialist Sandra Christensen, MSN, ARNP, compares the benefits and drawbacks among older antiobesity drugs and newer GLP-1RAs liraglutide and semaglutide 2.4 mg.
Antiobesity Medications: Expert Discusses Older, Newer Therapies
Obesity specialist Sandra Christensen, MSN, ARNP, details the differences between older antiobesity medications and newer GLP-1RAs liraglutide and semaglutide 2.4 mg.
Lorundrostat Phase 2 Trial Results Suggest Potential Efficacy Against Uncontrolled and Resistant Hypertension
The selective aldosterone synthase inhibitor will move into late stage clinical trials, a nod to the potential for a first-in-class agent targeting aldosterone.
Rise in GLP-1 Mimetic Demand Will Continue as Pluripotency Expands
The class of GLP-1 receptor agonists and similar agents, originally approved to treat type 2 diabetes, also reduce body weight and reduce CVD risk; what's next?
Daily Dose: Osteoarthritis Estimated to Affect Nearly 1 Billion by 2050
Your daily dose of clinical news you may have missed.
Daily Dose: Semaglutide 2.4 mg Benefits Patients with Heart Failure and Obesity
Osteoarthritis Projected to Affect Nearly 1 Billion by 2050, Obesity a Major Contributing Factor
Three key drivers of the perennial increase in OA prevalence are population growth, aging, and obesity, said authors of the analysis for the Global Burden of Disease study.