Empagliflozin Reduces HbA1c, FPG in Pediatric Population with Type 2 Diabetes
Empagliflozin is the first SGLT-2 inhibitor to demonstrate a statistically significant reduction in HbA1c in children and adolescents with type 2 diabetes.
9 Indicators of Personal Stress and How the 50 States Rank
From crime rates and credit scores to average health and hours worked in a week, find the 5 states that rank highest and the 5 lowest across 9 composite measures of stress.
Dementia: New Screening Tool to be Evaluated in Primary Care
The NIH has awarded $11 million for evaluation of a 5-minute, largely visual screening test for dementia intended for use in primary care practice.
Statin Treatment and Duration Associated with Reduced Risk of Hemorrhagic Stroke
Similar reduction in risk was reported for both lobar and nonlobar intracranial hemorrhage with longer statin treatment associated with greater protection, according to Danish investigators.
Daily Dose: Pediatric Obesity Treatment
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FDA Grants Priority Review to Pfizer’s RSV Vaccine Candidate for Older Americans
The FDA has granted priority review to a biologics license application for Pfizer’s respiratory syncytial virus vaccine candidate, RSVpreF, for adults aged ≥60 years.
FDA Authorizes Bivalent COVID-19 Vaccines as Booster Dose in Children Aged 6 Months to 5 Years
The FDA amended Pfizer and Moderna EUAs for updated COVID-19 vaccines to include children as young as age 6 months as holidays and winter weather approach.
Respiratory Virus Season Update: By the Numbers
Bempedoic Acid Meets Primary Endpoint in Key Cardiovascular Outcomes Trial: CLEAR
Approved in 2020 as Nexletol, bempedoic acid as the first ATP citrate lyase inhibitor and oral non-statin therapy to meet the MACE-4 primary endpoint.
FDA Grants Priority Review to sNDA for OTC Intranasal Naloxone HCl
The Agency's priority review of the prescription-OTC switch underscores the urgent need for broader access to the opioid overdose reversal agent.
Drug Overdose Deaths Reach Record High among Pregnant, Postpartum Women in US
Drug overdose deaths increased approximately 81% among pregnant and postpartum women in the US from 2017 to 2020, according to new research.
Butryate Supplementation May Support Pediatric Obesity Treatment
Findings from a new study suggest that supplementing standard care for obesity with butyrate helped reduce BMI, improve glucose metabolism, and reduce inflammation markers.
Daily Dose: Statin Prescribing in Primary Care
Influenza Update: Hospital Admissions Double During post-Thanksgiving Week
The inpatient flu census doubled after Thanksgiving travel and gatherings and ICU beds are full. More at-a-glance stats on Flu in the USA, here.
Daily Dose: Morning Exercise Reduces Risk for Cardiovascular Disease
Pfizer-BioNTech Seek EUA for Omicron Booster in Children Aged Under 5 Years
Pfizer and BioNTech submitted an application to the FDA for emergency use authorization of their omicron BA.4/BA.5-adapted bivalent COVID-19 vaccines in children aged 6 months to 4 years.
Tripledemic Virus Spread Could Jeopardize Holiday Season 2022, says CDC Director Walensky
Flu rates are up after the Thanksgiving holiday week, COVID-19 hospitalizations are increasing, and RSV may or may not be on the wane as Christmas approaches.
Statin Prescribing in Primary Care Boosted with EHR Prompts Plus Patient Alerts
An EHR prompt to a physician alone or in combination with a previsit patient prompt both increased statin prescribing in primary care but a patient prompt alone did not.
Daily Dose: Top Factors that Predict Long COVID
Morning Exercise Reduces Risk for Cardiovascular Disease in a New Study of UK Adults
Being most physically active in the late morning had a 16% decreased risk of coronary artery disease and a 17% decreased risk of stroke compared to midday.