Tirzepatide Cuts Risk of Progression to T2D by 94% Over 3 Years in Adults with Obesity, Overweight
Results of the 3-year SURMOUNT-1 study reflect the longest trial to date of tirzepatide in adults with overweight/obesity and risk for developing T2D.
PTSD May be a Modifiable Risk Factor for Poor T2D Outcomes
Younger US veterans with PTSD and type 2 diabetes who no longer met criteria for PTSD were less likely to initiate insulin and had reduced odds of mortality.
Cardiovascular Disease Prevention in Patients with Obesity: An Expert Perspective
Anila Chadha, MD, highlights key preventive strategies to reduce CVD risk in patients with obesity and how to tailor them to address individual patient needs.
Likelihood of a Dementia Diagnosis Highly Influenced by Geography: New Research
Investigators found as much as a 2-fold difference in being diagnosed with dementia across the US, even after controlling for common individual risk factors.
Cancer Deaths Among Men Projected to Increase 93% Globally by 2050, According to New Data
Researchers observed substantial disparities in burden by cancer type, age group, countries/territories, and a country's level of Human Development Index.
Undetected Mental Health Diagnoses in US Youth Suicides: Daily Dose
Your daily dose of the clinical news you may have missed.
Pfizer/BioNTech Combination Flu/COVID-19 Shot Misses Key Primary Phase 3 Endpoint
The influenza/COVID-19 combination did not prove noninferior to the comparator flu vaccine against influenza B, the companies reported.
Type 1 Diabetes: The High Price of Not Knowing
Primary care clinicians can screen at-risk individuals for type 1 diabetes with a single autoantibody panel. It pays to test and educate early, according to this author.
FDA Accepts Vertex NDA for Suzetrigine, Investigational Oral Nonopioid Analgesic for Acute pain
If approved the selective NaV1.8 pain signal inhibitor would reflect the first new class of pain management medication in more than 20 years.
Novel Blood Test for CRC Screening Receives FDA Approval: Daily Dose
Neffy, First Needle-Free Epinephrine, Fills a Deep Need for Patients, says Allergy Expert
The approval of neffy (epinephrine nasal spray) could help individuals and caregivers act sooner and feel safer treating a type 1 allergic reaction.
White Coat & Masked Hypertension: A Primary Care Guideline Topline
White coat and masked hypertension can be elusive and dangerous. Click through a topline look at recommendations from the 2017 ACC/AHA hypertension guidelines.
2024-25 Respiratory Virus Season: AAFP President on How to Get More Shots in Arms
Steven Furr, MD, discusses how communication between clinicians and patients is crucial to combatting vaccine hesitancy this upcoming respiratory virus season.
Diet High in Plant Fat Found to Reduce the Risk of Overall and CVD Mortality
Conversely, greater intake of animal-based fat was associated with an increased risk of overall and CVD mortality, authors reported.
Routine Laboratory Study Results Not Clinically Useful for Diagnosing Long COVID: New Analysis
Of the 25 routine lab tests studied, none proved clinically useful for diagnosing COVID-19, even among participants with a high long COVID symptom burden.
SGLT-2 Inhibitor Prescribing in the US is Failing People who Need them Most
No health system across the 28 analyzed in this study demonstrated appropriate SGLT2i prescribing for more than 25% of eligible individuals.
Lecanemab Will Be Evaluated in Preclinical Alzheimer Disease with Novel Study Design
The AHEAD study program will use plasma biomarker screening, novel PET agents, and other unique approaches to assessing lecanemab effect at the earliest stage of disease.
Suicide Rates Increasing among US Preteens, Particularly among Girls, Black and Hispanic Youth
Following a decrease, suicide rates among US preteens increased annually by 8.2% from 2008 to 2022, according to a recent cross-sectional study.
Shifting Trends in GLP-1RA Prescriptions: Daily Dose
5 Obesity Drugs Worth Watching: 2024-2025
Incretin analogues, an oral glucose formulation that targets endogenous nutrient-sensing pathways and a cannabinoid receptor 1 antagonist are in the new mix.