Daily Dose: High Blood Pressure While Lying Down Raises Risk for CVD Events
Your daily dose of the clinical news you may have missed.
Daily Dose: "Night Owls" Less Healthy, at Higher Risk for T2D
Moderna Investigational Influenza Vaccine Meets Safety, Efficacy Endpoints Across Phase 3 Trials
Moderna reported at its annual R&D day that its flu vaccine has met primary phase 3 endpoints and that phase 1/2 data show higher HIA titers vs Fluzone HD.
Dupilumab Potent Against Uncontrolled COPD with T2 Inflammation: BOREAS Trial Update
Reduced exacerbations, improved lung function, increased QoL, and less use of systemic corticosteroids underscore dupilumab's effects against type 2 inflammation.
One in 5 US Adults Mixes Alcohol with Alcohol-Interactive Medications
Primary Care Alert: Risky alcohol use in the past year was found highest among persons taking benzodiazepines, followed by those taking opioids, and taking antiepileptics.
Opioids, Pain, and Sleep: How Do They Interact With Each Other?
A recent study of patients with chronic low back pain sheds light on the association between sleep and opioid use on pain severity and interference.
Daily Dose: More Steps a Day Linked to Better Health for Patients with Heart Failure
Your daily dose of clinical news you may have missed.
Blood Pressure Treatment Targets in Adults with Hypertension: A Guideline Topline
This guideline topline summary of recommendations for treating hypertension in adults is adapted from the American Academy of Family Physicians clinical guideline.
PCOS Ups Risk of Maternal, but Not Neonatal Adverse Outcomes in Women with T2D in Pregnancy
Women with PCOS and T2D in pregnancy were at greater risk for high insulin requirements, excess weight gain, and worsening of pregestation hypertension if treated with metformin.
Antiobesity Medications: Expert Discusses Older, Newer Therapies
Obesity specialist Sandra Christensen, MSN, ARNP, details the differences between older antiobesity medications and newer GLP-1RAs liraglutide and semaglutide 2.4 mg.
Lorundrostat Phase 2 Trial Results Suggest Potential Efficacy Against Uncontrolled and Resistant Hypertension
The selective aldosterone synthase inhibitor will move into late stage clinical trials, a nod to the potential for a first-in-class agent targeting aldosterone.
Daily Dose: COVID-19 Vaccination Decreases Symptoms of Long COVID
Rise in GLP-1 Mimetic Demand Will Continue as Pluripotency Expands
The class of GLP-1 receptor agonists and similar agents, originally approved to treat type 2 diabetes, also reduce body weight and reduce CVD risk; what's next?
Evening Chronotype in Women Linked with Unhealthy Lifestyle, Increased Risk for Type 2 Diabetes
Women with an evening vs morning chronotype were 54% more likely to have unhealthy lifestyles that in turn accounted for a significant increased risk for diabetes.
Remote Bilingual Program Proves Effective in Controlling Blood Pressure in Underserved Population
New research presented at Hypertension 2023 showed a novel digital bilingual hypertension control program improved BP control rates by more than 30%.
Daily Dose: Worldwide Burden of Atrial Fibrillation Doubled Over 30 Years
It's High Time to Normalize Pre-Visit Lab Testing
Research demonstrates that discussing test results face-to-face with patients during office visits is beneficial for patient and clinician, according to family physician Andrew Carroll, MD.
FDA Approves Updated COVID-19 Monovalent Vaccines for 2023-2024
As COVID-19 hospitalizations increase at the opening of the respiratory virus season, the first "seasonal" vaccine against the virus is ready for roll-out, says the FDA.
Seen in the ED Quiz: Severe Wrist and Knee Pain in an Older Man
The man in his early 70s complains of leg pain lasting a month and of arm pain that came on about 1 week ago. Does the x-ray offer a clue to a diagnosis?
Parents Negative Beliefs about HPV Vaccination Create Barriers to Adolescent Uptake, a New Study Suggests
Parent's stigmatizing beliefs about the HPV vaccine may keep them from communicating openly with teens' clinicians, creating barriers to getting shots in arms.