The CASCADE study found the biomarker of inflammation CRP associated with higher COPD symptom burden.

Primary care drugs were approved in nearly every month of 2016. This top-line slide show highlights 20 you should know about.

Opioid prescribing is rarely straightforward. The well respected Opioid Calculator from colleagues "down under" has simplification and safety built in.

CDC: Some preventable causes of death have declined, but these accounted for almost two-thirds of deaths from all causes.

The diagnosis of trichotillomania seemed certain, despite lack of supporting history. It turned out to be about 50% wrong.

A 10-month history of progressive swelling below the knee makes this 12-year-old's case an ideal stop on the medical mystery tour.

A new 5-question COPD assessment tool may help identify more serious disease earlier in the primary care setting.

It looked very much like dermatomyositis, but there were no signs of muscle weakness. What would be in your differential diagnosis?

New evidence-based clinical practice guidelines offer some strong-and not so strong-recommendations for effective gout diagnosis and treatment.

Scroll through this compact slide show for review of gaps in US adult vaccination practice and how primary care can help fill them.

For the busy primary care physician, the AHRQ ePSS delivers immediate, patient-specific screening recommendations.

The HEEADSSS psychosocial interview is a comprehensive aid to help discuss with adolescents social and emotional aspects of life that may impact physical health.

The 16-year-old is upset by a new outbreak of “acne” and the prom is in 2 weeks. But is it acne? And what’s that bruise?

A young naval recruit presents with a cluster of symptoms that may sound familiar. Get more clues and a close look at the rash, here.

Do doctors’ politics affect treatment decisions on, for example, drug use, firearms, and sexual behavior? Do yours?

Onset of illness was acute; fever is high and rash is widespread. Exam is performed in isolation. Your Dx?

Brothers present with residual findings from a bad bout of lower GI distress. Their tongues will speak for themselves. What's your Dx?

An 8-year-old boy was seen in the ED for sudden, extreme tenderness of the soles of his feet. He now sees you, in primary care.

A few days after a homecoming party a 17-year-old girl presents with a pruritic rash at her waist and on her upper arms. What went on?

USPSTF recommendations for TB screening in primary care and a challenge to the 2-state TB paradigm are some of the latest.