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6 Questions on Severe Uncontrolled Asthma: Key Characteristics for Primary Care


The clinical challenge in treating severe uncontrolled asthma remains complex even as novel biologic therapies continue to emerge.

Authors of a comprehensive review and international expert opinion published in the Journal of Allergy and Clinical Immunology: In Practice, present and discuss a set of clinical variables they identify as most important to managing severe uncontrolled asthma in adult patiens and that help optimize the choice of specific biologic treatment.

The following 6 questions reflect the expert opinion and also offer a brief overview for primary care clinicians of the key factors that support treatment decisions.

Reference: Buhl R, Bel E, Bourdin A, et al. Effective management of severe asthma with biologic medications in adult patients: a literature review and international expert opinion. J Allergy Clin Immunol. 2022;10:422-432. doi:10.1016/j.jaip.2021.10.059

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