• Heart Failure
  • Cardiovascular Clinical Consult
  • Adult Immunization
  • Hepatic Disease
  • Rare Disorders
  • Pediatric Immunization
  • Implementing The Topcon Ocular Telehealth Platform
  • Weight Management
  • Monkeypox
  • Guidelines
  • Men's Health
  • Psychiatry
  • Allergy
  • Nutrition
  • Women's Health
  • Cardiology
  • Substance Use
  • Pediatrics
  • Kidney Disease
  • Genetics
  • Complimentary & Alternative Medicine
  • Dermatology
  • Endocrinology
  • Oral Medicine
  • Otorhinolaryngologic Diseases
  • Pain
  • Gastrointestinal Disorders
  • Geriatrics
  • Infection
  • Musculoskeletal Disorders
  • Obesity
  • Rheumatology
  • Technology
  • Cancer
  • Nephrology
  • Anemia
  • Neurology
  • Pulmonology

Acute Hepatitis C: To Treat or Not to Treat?


Should acute infection with hepatitis C virus (HCV) be treated? If yes, what is the recommended treatment?

Should acute infection with hepatitis C virus (HCV) be treated? If yes, what is the recommended treatment? -- Percy Kepfer, MD Fort Pierce, Fla

Once acute HCV infection has been diagnosed, monitor the patient. In those who spontaneously clear an acute infection, clearance usually occurs within 3 months of the known onset of hepatitis. If HCV viremia has not cleared by 3 months, it is highly likely that the infection will become chronic.

Although no randomized controlled trials have addressed this question, I recommend a 3- to 6-month course of peginterferon-based therapy (with or without ribavirin) in those patients who have failed to clear acute infection. Success rates in this setting (ie, rates of sustained viral clearance) approach 90%. The importance of early treatment is clear: these success rates vastly eclipse those seen in patients with chronic infection.

-- Raymond T. Chung, MD Associate Professor of Medicine Harvard Medical School Director of Hepatology Medical Director, Liver Transplant Program Massachusetts General Hospital Boston

Related Videos
Infectious disease specialist talks about COVID-19 vaccine development
COVID 19 impact on healthcare provider mental health
Physician mental health expert discusses impact of COVID-19 on health care workers
© 2024 MJH Life Sciences

All rights reserved.