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Knee Knots in a Young Girl: What's Your Diagnosis?


Painful red lesions on the shins. Trauma? Tumor? Inflammation? The diagnosis is in the detailed differential you'll follow in this slide show.

Polly is 6-years-old and is admitted to hospital for painful red nodules on her shins that have been present for 2 weeks. She has no fever, has not been immunized recently, and has no travel history. She had a sore throat a few weeks ago but that has resolved. What's causing the painful lesions on her legs?It's another in our series of thought-provoking cases from Dr Jonathan Schneider. The well- considered differential diagnosis is key to resolving his cases and he walks you deliberately through the details. Trauma? Tumor? Inflammatory condition? Follow the slides above and find out.   


Suggested reading

 â–º Schwartz RA, Nervi SJ. Erythema nodosum: a sign of systemic disease. Am Fam Physician. 2007;75:695-700.

 â–º Requena L, Sánchez Yus E. Erythema nodosum. Semin Cutan Med Surg. 2007;26:114-125.

 â–º Kakourou T, Drosatou P, Psychou F, Aroni K, Nicolaidou P. Erythema nodosum in children: a prospective study. J Am Acad Dermatol 2001;44:17-21.

 â–º Labbe L, Perel Y,  Maleville J, Taieb A. Erythema nodosum in children: a study of 27 patients. Pediatr Dermatol 1996;13:447-450.

 â–º Requena L, Requena C. Erythema nodosum. Dermatol Online J. 2002;8(1):4.



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