Laxatives With Antraquinones Associated With Melanosis Coli
August 16, 2013
Laxatives that contain antraquinones can induce a dark pigmentation in the colonic mucosa.
The finding of pigmented mucosa-melanosis coli-on colonoscopy is associated with which of the following laxatives?
A. Senna B. Docusate sodium (Colace) C. Polyethylene glycol (Miralax) D. Milk of magnesia
Correct answer: A
Laxatives that contain antraquinones (eg, senna) can induce a dark pigmentation in the colonic mucosa. The cecum and rectum are the most commonly affected sites. Despite its appearance on colonoscopy, melanosis coli is a benign finding. The other laxatives do not cause this condition.
