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Opinion|Videos|January 20, 2025

Overview of Teplizumab for Delaying Onset and Progression of Type 1 Diabetes

Author(s)Javier Morales, MD, FACP, FACE , Shira Eytan, MD, FACE, Bethany Kinsey, NP

Panelists discuss how teplizumab, the first FDA-approved disease-modifying therapy for Type 1 diabetes, can delay disease onset by targeting CD3+ T cells and preserving beta cell function in high-risk individuals.

Episodes in this series

4 experts are featured in this series.

EP. 1 Living with Type 1 Diabetes

4 experts are featured in this series.

EP. 2 Screening Guidelines for Type 1 Diabetes

4 experts are featured in this series.

EP. 3 Stages and Symptoms of Type 1 Diabetes

4 experts are featured in this series.

EP. 4 Impact of Delayed Intervention in Stage 2 Type 1 Diabetes

4 experts are featured in this series.

EP. 5 Types of Antibody Screening Tests for Type 1 Diabetes

4 experts are featured in this series.

EP. 6 Overview of Teplizumab for Delaying Onset and Progression of Type 1 Diabetes

4 experts are featured in this series.

EP. 7 Patient Selection For Teplizumab and Infusion Process

4 experts are featured in this series.

EP. 8 Final Thoughts on Identifying and Managing Patients with T1D

Newsletter

Enhance your clinical practice with the Patient Care newsletter, offering the latest evidence-based guidelines, diagnostic insights, and treatment strategies for primary care physicians.

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26th Annual International Lung Cancer Congress

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IgAN Case Files: Real Conversations, Evolving Evidence

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Navigating Ocular Toxicities: A Multidisciplinary Roadmap for Managing Adverse Events in Targeted Cancer Therapy

Basil Williams, MD; Maura Di Nicola, MD

(CME Track) Antibody–Drug Conjugates in Oncology: The Essentials of AE Management for Better Patient Outcomes

(CME Track) Antibody–Drug Conjugates in Oncology: The Essentials of AE Management for Better Patient Outcomes

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Elizabeth Burgener, MD; Leah A. Cohen, MD; William R. Hunt, MD, FAAP, FACP, FSSCI

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Charu Aggarwal, MD, MPH, FASCO; Zofia Piotrowska, MD, MHS

9th Annual School of Nursing Oncology™

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(CME Track) Seeing the Signs: Multidisciplinary Strategies to Manage Ocular Toxicities Associated With Cancer Therapies

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20th Annual New York Lung Cancers Symposium®

20th Annual New York Lung Cancers Symposium®

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43rd Annual CFS®: Innovative Cancer Therapy for Tomorrow™

43rd Annual CFS®: Innovative Cancer Therapy for Tomorrow™

Benjamin P. Levy, MD; John O. Mascarenhas, MD; Tiffany A. Traina, MD, FASCO

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Precision in Practice: Advancing Prostate Cancer Care With PSMA-Directed Radioligand Therapy

Scott T. Tagawa, MD, MS, FASCO, FACP; Himisha Beltran, MD; Neeta Pandit-Taskar, MD, MBA

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Biomarker Testing in HER2+ GEA: Diagnosis and Treatment Implications

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Navigating the Adverse Event Landscape in HER2+ GEA Therapy

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ISGIO 2025: Esophageal and Gastric Cancer

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Joanna Mycek, MD; M. Bassam Sonbol, MD; Matthew R. Strickland, MD; Vivian E. Strong, MD, FACS

ISGIO 2025: Hepatobiliary Cancers

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Natasha Bahri, MD, MSc; Ashton A. Connor, MD, PhD; James J. Harding, MD; Daneng Li, MD; Shubham Pant, MD, MBBS

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Oncology Town Hall: Shaping the Future of ALL Treatment Through Innovation in T-Cell Therapies

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Expert Illustrations & Commentary: Visualizing the Role of Novel Muscarinic Agents in the Management of Schizophrenia

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ISGIO 2025: Early-Stage Colorectal Cancer

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Bridging Regional Challenges in Retinal Disease Management: Applying Advanced Anti-VEGF Therapy in Community Practice - California

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4th Annual International Congress on Pediatric Oncology

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Jacqueline M. Kraveka, DO

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Screening for Type 1 Diabetes and Delaying Its Onset—An Innovative View

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(CME Track) Tackling Oncologic Emergencies in Patients Treated With High-Dose Methotrexate

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Burst CME™ in Gaucher Disease: Patient Evaluation and Management

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Steven Fein, MD

Optimizing Multidisciplinary Care in TGCT

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Burst CME™: Disease-Modifying vs. Curative Therapy – Which Way to Go in Sickle Cell Disease?

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Matthew Heeney, MD; Biree Andemariam, MD

Empowering HIV Management: Evidence-Based Prevention and Treatment Strategies

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Onyema Ogbuagu, MD, FACP, FIDSA

Optimizing Lipid-Lowering Strategies for ASCVD Risk Reduction: Bridging the Gap in Treatment Intensification

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Erin D. Michos, MD, MHS; Nihar Desai, MD, MPH

Collaborating Across the Continuum™: Integrating Novel Therapies Into Multidisciplinary Treatment Plans for Generalized Myasthenia Gravis

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Medical Crossfire®: The Who, When, and How of TROP2-Targeting ADCs, ICIs, and PARP inhibition in Triple-Negative Breast Cancer

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Hope S. Rugo, MD; Alison K. Conlin, MD; Marleen Kok, MD, PhD; Heather McArthur, MD, MPH

From Gene to Gut: Understanding TL1A’s Function in IBD Evolution

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Jordan E. Axelrad, MD, MPH, FACG

Cases and Conversations™: Navigating CKD and Heart Failure in T1D and T2D—Applying the Latest Guidelines and Evidence

Cases and Conversations™: Navigating CKD and Heart Failure in T1D and T2D—Applying the Latest Guidelines and Evidence

Stephen J Greene, MD; Anuradha Lala-Trindade, MD

Burst CME™: Recognizing Lupus Nephritis—From Timely Diagnosis to Appreciating the Underlying Mechanisms of Disease

Burst CME™: Recognizing Lupus Nephritis—From Timely Diagnosis to Appreciating the Underlying Mechanisms of Disease

Michelle Petri, MD, MPH; Shivani Garg, MD, PhD

Medical Crossfire™: Navigating the Expanding Arsenal of Endocrine Therapies for HR+/HER2- Metastatic Breast Cancer – How Can PROTAC ER Degradation Shift the Standard?

Medical Crossfire™: Navigating the Expanding Arsenal of Endocrine Therapies for HR+/HER2- Metastatic Breast Cancer – How Can PROTAC ER Degradation Shift the Standard?

William J. Gradishar, MD, FASCO, FACP; Stephanie L. Graff, MD, FACP, FASCO; Cynthia X. Ma, MD, PhD

Burst CME™: Optimal Management of Complications of Sickle Cell Disease

Burst CME™: Optimal Management of Complications of Sickle Cell Disease

Matthew Heeney, MD; Deepika S, Darbari, MD

Burst CME™: Staying Informed and Up-To-Date on the Treatment of Lupus Nephritis

Burst CME™: Staying Informed and Up-To-Date on the Treatment of Lupus Nephritis

Michelle Petri, MD, MPH; Shivani Garg, MD, PhD

When Mites Meet Their Match: Empowering Patients With Targeted Treatment for 𝘋𝘦𝘮𝘰𝘥𝘦𝘹 Blepharitis

When Mites Meet Their Match: Empowering Patients With Targeted Treatment for 𝘋𝘦𝘮𝘰𝘥𝘦𝘹 Blepharitis

Mile Brujic, OD, FAAO; Pierce Kenworthy, OD, FAAO; Blair Lonsberry, MS, OD, MEd, FAAO

Community Collab: The Evolving Role of FcRN Inhibitors in the Management of Generalized Myasthenia Gravis (gMG)

Community Collab: The Evolving Role of FcRN Inhibitors in the Management of Generalized Myasthenia Gravis (gMG)

James F. Howard Jr, MD, FAAN; Tuan Vu, MD

Burst CME™: Burden of Sickle Cell Disease

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Cases & Conversations™: Unmasking Epithelioid Sarcoma – Enhancing Early Diagnosis and Multidisciplinary Care

Cases & Conversations™: Unmasking Epithelioid Sarcoma – Enhancing Early Diagnosis and Multidisciplinary Care

Mark Agulnik, MD; Mrinal M. Gounder, MD; Sandra D’Angelo, MD; Sujana Movva, MD

Advances in™: Lipoprotein(a) as a Target for ASCVD Risk Reduction – Updates for Clinical Practice

Advances in™: Lipoprotein(a) as a Target for ASCVD Risk Reduction – Updates for Clinical Practice

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Expert Illustrations & Commentary: Visualizing Novel Therapeutic Targets for Patients with Major Depressive Disorder

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The Presbyopia-Correcting and Toric IOL Playbook: Game-Changing Surgical Strategies to Enhance Patient Outcomes

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The Rise of Novel HER2-Targeting Therapies in GEA: Mechanisms and Clinical Data

The Rise of Novel HER2-Targeting Therapies in GEA: Mechanisms and Clinical Data

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Advances In™: A Glimpse Into the Future Care of Platinum-Resistant Ovarian Cancer

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Show Me the Data™: Personalizing First-Line and Maintenance Therapy in HER2+ Metastatic Breast Cancer to Extend Survival and Elevate Quality of Life

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Beyond Primary End Points: Digging Into Randomized and Real-World Data to Guide Challenging Treatment Decisions in HR+/HER2− Metastatic Breast Cancer

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Medical Crossfire®: Mastering the Nuances of Early-Stage HR+/HER2- Breast Cancer—Expert Perspectives on Applying Modern Treatment Paradigms

Medical Crossfire®: Mastering the Nuances of Early-Stage HR+/HER2- Breast Cancer—Expert Perspectives on Applying Modern Treatment Paradigms

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From Frontline to Heavily Pretreated HR+/HER2- Metastatic Breast Cancer: Expert Perspectives on Optimizing the Expanding Treatment Armamentarium

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From Suspicion to Stabilization: Early Recognition and Treatment of Paraneoplastic LEMS

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(CPE Track) SoCal Psych 2025: Overcoming Barriers to Long-Acting Injectable Agents in Schizophrenia

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