Risk of CKD Progression Lower in Women vs Men: Findings from the CRIC Study

January 17, 2019

Authors of the CRIC study found sex-related disparities in chronic kidney disease progression. Scroll through our slideshow to get the highlights. 

Men in the US have a higher incidence of end stage renal disease (ESRD), despite a lower incidence of chronic kidney disease (CKD) vs women. Men may have more rapid progression of CKD vs women, though findings from previous studies have been inconsistent. Now, results of a large, prospective investigation show that women with CKD have a significantly lower risk of developing ESRD, 50% eGFR decline, progression to CKD stage 5, and death vs men. Taken together, the findings of this study by Ricardo and colleagues suggest a sex-related disparity in CKD progression and mortality, though additional studies are needed to pinpoint the factors underlying the sex-related differences.