Safety of Tiotropium in Children with Persistent Asthma

February 20, 2018
Veronica Hackethal, MD
Veronica Hackethal, MD

Results of the first study to evaluate use of the adult COPD drug in children age 5 years and younger lay fertile ground for future trials.

Results of the first study to evaluate use of tiotropium as add-on medication to inhaled corticosteroids in children age 5 years and younger found fewer asthma exacerbations vs placebo and similar effects on asthma improvement as placebo. Click through the short slide show above for highlights. Source: Vrijlandt EJLE, El Azzi G, Vandewalker M, et al. Safety and efficacy of tiotropium in children aged 1-5 years with persistent asthmatic symptoms: a randomised, double-blind, placebo-controlled trial. Lancet Respir Med. 2018 Jan 17. pii: S2213-2600(18)30012-2. doi: 10.1016/S2213-2600(18)30012-2.