Safety of Tiotropium in Children with Persistent Asthma

February 20, 2018

Results of the first study to evaluate use of the adult COPD drug in children age 5 years and younger lay fertile ground for future trials.

Results of the first study to evaluate use of tiotropium as add-on medication to inhaled corticosteroids in children age 5 years and younger found fewer asthma exacerbations vs placebo and similar effects on asthma improvement as placebo. Click through the short slide show above for highlights. Source: Vrijlandt EJLE, El Azzi G, Vandewalker M, et al. Safety and efficacy of tiotropium in children aged 1-5 years with persistent asthmatic symptoms: a randomised, double-blind, placebo-controlled trial. Lancet Respir Med. 2018 Jan 17. pii: S2213-2600(18)30012-2. doi: 10.1016/S2213-2600(18)30012-2.