Commentary|Videos|October 29, 2025

When Should Mammography Begin? Donna Plecha, MD, on Differing Breast Cancer Screening Guidelines

Fact checked by: Grace Halsey

Early breast cancer screening at age 40, especially with 3D mammograms, significantly improves survival rates and quality of life, according to Dr Plecha.

Screening recommendations for breast cancer vary among professional societies, creating confusion for both clinicians and patients. Dr Plecha outlines where the major guidelines—from NCCN, ACR, and USPSTF—align, emphasizing that starting annual mammography at age 40 remains the strategy most strongly supported by evidence for saving lives.

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