Grace Halsey

Risk of mortality from ALD and MetALD was significantly higher among women even though both phenotypes were more prevalent among men, a new study reveals.

Oral VX-548 has the potential to fill the gap between drugs that are tolerable but lack efficacy and opioids with therapeutic efficacy but known risks, according to Vertex.

Overweight and obesity affect the 50 states and DC in different ways and to varying degrees but no state is unaffected. The short slide show offers insights at-a-glance.

Measles cases are reported in 6 states, which is not a surprise to one pediatrician who points to the ongoing consequences of falling vaccination rates.

Low-dose calcium supplementation with 500 mg/day may be as protective against poor pregnancy outcomes as the WHO-recommended dose of 1500 mg/day.

The risk of asthma and poor outcomes was even greater among children with both conditions than among adults in this first study to compare the 2 populations.

The investigational combination opioid from Ensysce Biosciences is designed to deter abuse as well as prevent accidental or intentional overdose, the company said.

Heart disease has been the primary cause of death in the US for the last century, and yet 51% of adults do not recognize the fact.

Already high rates of readmission and mortality at 30 days rose significantly higher at 90 days, according to this National Readmissions Database review.

Dupilumab is the first agent approved to treat EoE in this vulnerable pediatric population.

Among more than 1.5 million persons hospitalized for COVID-19, a history of Crohn disease or ulcerative colitis significantly increased risk for poor outcomes.

"A meaningful percentage" of individuals with Crohn disease are treated during maintenance with biologic doses ≥20%higher than recommended in FDA labeling.

Adolescents with overweight or obesity and baseline HbA1c 6.3%-6.4% were at 72-fold greater risk for T2D than those with HbA1c of 5.5%, a new cohort study finds.

Targeting "impermissible" barriers created to no-cost contraception required by the ACA, the HHS guidance follows the Biden-Harris June 2023 Executive Order on the issue.

The Boxed Warning reflects FDA research into severe adverse events including hospitalization and death in persons with CKD treated with denosumab.

Remission of T2D, regardless of duration of remission, was associated with reduced risk of diabetes-related CKD and CVD in a post hoc analysis of Look AHEAD.

In persons with COPD, use of the anticonvulsants was linked to a 39% increase in risk of severe disease exacerbation requiring hospital admission, study authors reported.

When it comes overweight, obesity, and prescription drugs for weight loss, these results from the National Poll on Healthy Aging suggest older US adults need guidance.

The protective effect of bempedoic acid appeared to increase with the number of CV events a study participant experienced, according to study authors.

This second shelf-life extension for the OTC naloxone hydrochloride 4 mg spray continues the FDA's campaign to prevent drug overdose and related fatalities.

Changes to the ACIP adult schedule include new Notes on the RSV vaccines and updates to Notes on flu vaccination, COVID-19 vaccination, and the pentavalent MenB shot.

Use of nonprescribed weight loss products was higher among girls than boys globally and led by diet pills, followed by laxatives and diuretics, a meta-analysis found.

Each additional month of breastfeeding beyond 3 months correlated with a significantly lower child BMIz, especially for mothers identified as overweight or obese.

Screening for fibrosis in persons at risk of ALD and MASLD led to sustained improvements in lifestyle, eg, reduced alcohol consumption, weight loss, and increased exercise.

More than half of adults with moderate to severe UC maintained clinical and endoscopic remission at 4 years; nearly all no longer required corticosteroids, authors reported.

While the FDA's preliminary evaluation has not surfaced evidence of a link, the agency says it "cannot definitively rule out that a small risk may exist," and so will continue research.

Use of dupilumab also eliminated the need for use of a rescue inhaler in more than one-third of treated patients and the number of inhalations needed for others.

The risk of severe CV events, including leading to death, was greatest in the first week following an exacerbation but remained significantly elevated 1 year later.

The novel nonhormonal compound significantly reduced vasomotor symptoms and sleep disturbance while improving quality of life, according to findings.

Cannabis use during pregnancy, particularly continued use beyond the first trimester, was associated with SGA birth, still birth, and hypertensive disorders of pregnancy, authors reported.