Urinary protein levels may be an early marker of future cognitive decline in patients with type 2 DM and normal kidney function, according to a new study.
OSA is not simply a marker for poor health but is an independent risk factor for open-angle glaucoma. Both conditions affect millions worldwide.
The ankle-brachial index is a noninvasive screening tool that can improve cardiovascular event risk stratification.
Elevated levels of the biomarker C-reactive protein in patients with HIV infection increased the risk of MI approximately 2-fold.
A genetic analysis questions the benefits of raising HDL-C levels to reduce the risk of MI and of the value of HDL-C as a surrogate marker of risk.
With genetic tests rapidly entering medical practice, and some patients even ordering them on their own, the NIH has launched a Genetic Testing Registry to help doctors interpret and follow up on these tests. In this interview, the director of the new Genetic Testing Registry tells why you need it, and what's there for your reference.
1. Giovannucci E, Stampfer MJ, Krithivas K, et al. The CAG repeat within the androgen receptor gene and its relationship to prostate cancer. Proc Natl Acad Sci USA 1997;94(7):3320-3323
Systemic inflammation has been identified as a risk factor for the development of heart failure in population studies. In the 5-year prospective MESA study, researchers from Johns Hopkins Hospital in Baltimore recorded a baseline nonspecific marker of systemic inflammation, C-reactive protein (CRP).
Researchers from Massachusetts General Hospital in Boston presented results from the PROTECT (ProBNP Outpatient Tailored Chronic Heart Failure) study. NT-proBNP (b-type natriuretic peptide) is a biomarker released from myocardial tissue in response to high levels of wall stretch and has been studied as a marker for decompensated systolic heart failure.
Biomarker: Putative molecular indicator of a specific biological state.1 Some biomarkers, called surrogate endpoints, are used as substitutes for actual clinical endpoints such as incidence of disease or death.2