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FDA approved baxdrostat for adults with hypertension not controlled on other agents, adding a new aldosterone-targeting option.

A 5-day course of ensitrelvir reduced symptomatic COVID-19 risk by 67% after household exposure in the phase 3 SCORPIO-PEP trial.

DDW 2026: Jennifer Schmaus, PhD, on how mental health screening in IBD clinics may improve engagement with psychogastroenterology services.

Despite waning direct impact of COVID-19, US pregnancy-related mortality remains higher than before the pandemic, driven by persistent cardiovascular, infectious, and hemorrhagic causes.

A large claims analysis suggests most US patients with prediabetes receive annual diabetes screening, although methods were not peer reviewed.

Colombel discusses 4-year LUCENT findings showing sustained disease clearance and a favorable long-term safety profile with mirikizumab in UC

Global experts have redefined PCOS as PMOS, spotlighting metabolic and heart risks to speed diagnosis, reduce stigma, and improve care.

Leslie Citrome, MD, on new NEI Spring Congress data on adjunctive lumateperone for major depressive disorder and how clinicians can weigh efficacy, tolerability, and next-step treatment decisions.

MR-100A-01 weekly contraceptive patch data will be presented ahead of an FDA decision on the investigational lower-estrogen product.

Highlights include time-efficient strategies for primary care clinicians to identify, assess, and treat GSM and other sexual health concerns during menopause.

ACOG 2026: Kathryn Miele, MD, discusses syphilis screening in pregnancy and how clinicians can reduce stigma around testing.

ACOG 2026: Kathryn Miele, MD, discusses syphilis titer interpretation, discordant results, partner treatment, and practical resources for primary care clinicians.

The approval indicates ocrelizumab for RRMS in patients older than 10 years who weigh 55 pounds or more and is supported by data from the OPERETTA II study.

Highlights include clinical gaps in menopause care, postpartum prevention, cervical cancer screening, pregnancy-related infection, and GLP-1 RA exposure.

Pneumococcal vaccination in pregnancy remains underused in high-risk patients. Maria Marcos, MD, reviews new data, barriers to uptake, and practical vaccination steps for primary care.

Bariatric surgery was associated with lower 2-year costs than GLP-1 therapy in adults with obesity and type 2 diabetes, according to new real-world data.

Jill Liss, MD, outlines how updated evidence, risk stratification, and newer nonhormonal agents can help PCPs confidently manage VMS in everyday practice.

ACOG 2026: James A. Simon, MD, discusses off-label evidence for elinzanetant in breast cancer survivors on anti-estrogenic therapy.