There’s a new way to lower LDL cholesterol levels-by approximately 60% to 80%. Studies unveiled at the 2012 ACC meeting found that an injectable monoclonal antibody, when added to statin therapy cuts LDL cholesterol levels far in excess of what can be achieved with statin therapy alone. Drs Christopher Cannon and Payal Kohli discuss.

The FDA will launch an intensive review of data on the safety of metal-on-metal hip implants in June, responding to yet more evidence that they present a high risk of failure and revision surgery. Listen as orthopedic surgeon William Maloney of Stanford University School of Medicine discusses the risks and the realities of hip replacement today.

Patients with type 2 diabetes should be receiving statin therapy, but many patients who would benefit from these agents are not taking them-and not reaching target lipid levels. A recent study shows that timing of statin initiation can make a difference. Here to put the issue into perspective are Drs Christopher Cannon and Payal Kohli.

Drinking sugar-sweetened beverages is known to cause weight gain and heightens the risk of type 2 diabetes mellitus. Here to put the issue into perspective are Drs Christopher Cannon and Payal Kohli.

Statins have been shown to significantly reduce the risk of heart attacks, heart disease and death. But this week, the FDA decided that the package inserts of the various statins must now include a warning that these agents may raise blood glucose levels and that they can cause memory loss. Here to put this issue into perspective are Drs Christopher Cannon and Payal Kohli.

Data from a long-term prospective study reveal that for many older women, the pace of bone mass deterioration takes place on the scale of decades, not single years. Here, the lead author of the study describes how to interpret the results to choose the date for your own patient's next bone density test.

In his second podcast, Dr Louis Kuritzky discusses the classes of incretin-based therapies now available for patients with type 2 diabetes mellitus.

Louis Kuritzky, MD, talks about this relatively new treatment option.

What exactly are the new guidelines for vaccinating boys against HPV infection-and why is this development good news for both men and women?

In many patients, episodic migraines increase in frequency and transform into a refractory pattern.

What are the factors that underlie the transformation of episodic migraine to refractory migraine? Dr Susan Hutchinson explains.

How does the chronic care model of diabetes care differ from the acute care model-and how might this approach work for you and your patients?

Dr Robert Gabbay discusses strategies to improve patient compliance with insulin therapy.

Measles is making a comeback . . . yet again . . . in the United States.

Presidential candidate Michelle Bachmann recently made the unsubstantiated comment on national TV that the HPV vaccine has “very serious consequences” and that it can cause mental retardation.

A bad ("sick" or killer) headache is usually a migraine if underlying organic causes of pain are ruled out.

How can you determine whether your patient with newly diagnosed diabetes has type I or type II disease?

In Part 2 of this podcast series, Dr Smith continues his discussion of the practice of nonsuicidal self-injury in adolescents.

In this podcast, Dr Smith discusses the practice of nonsuicidal self-injury in adolescents-cutting, burning, self-hitting or banging, scratching, interfering with wound healing-may be increasing.