Infectious Disease

The mRNA vaccine returned efficacy of 83.7% against RSV-associated lower respiratory tract disease defined by ≥2 symptoms and of 82.4% against disease defined by ≥3 symptoms.

Overall dyspnea was the most common symptom of long COVID in the first year after infection, according to the nationwide retrospective cohort study.

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Direct-acting antiviral treatment was independently associated with a lower risk of mortality and liver and nonliver outcomes in a large study of adults with chronic hepatitis C.

Among the CDC vaccine advisory group's recommendations are adding COVID-19 vaccines to the Vaccine for Children program and allowing PCV20 shots for those who previously received PCV13.

Lenacapavir is the first of a new class of antiretrovirals, and it is indicated for persons with multidrug resistance, intolerance, or safety considerations.

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One study showed the boosters provide significant protection against hospitalization and ED care and the other found vaccine effectiveness of 84% in older adults.

Physiatrist Monica Verduzco-Gutierrez, MD, highlights the state of long COVID management in the US and says primary care is crucial in diagnosing and treating the new condition.

The vaccination campaign in the US also has prevented more than 18 million hospitalizations and saved $1 trillion in medical costs, according to a modeling study.

The FDA amended Pfizer and Moderna EUAs for updated COVID-19 vaccines to include children as young as age 6 months as holidays and winter weather approach.

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The inpatient flu census doubled after Thanksgiving travel and gatherings and ICU beds are full. More at-a-glance stats on Flu in the USA, here.

She reports cough and persistent escalating fever x2 weeks, headache but no neck stiffness. Tachycardia and mild skin pallor seen on PE. What do the lab tests tell you?

Pfizer and BioNTech submitted an application to the FDA for emergency use authorization of their omicron BA.4/BA.5-adapted bivalent COVID-19 vaccines in children aged 6 months to 4 years.

Flu rates are up after the Thanksgiving holiday week, COVID-19 hospitalizations are increasing, and RSV may or may not be on the wane as Christmas approaches.

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Analysis of an online survey in the UK found women vs men and higher vs lower BMI were associated with greater likelihood of developing long COVID.

Respiratory syncytial virus is an age-old winter foe that could affect many of your patients this year. Take a minute and scan these facts for a refresher.

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One in 7 parents have not discussed vaccines with their child's primary clinician during the 2-year pandemic period, according to a CS Mott Children's Hospital poll.

Overall flu activity is at a 10-year high, according to the CDC's most recent influenza surveillance report, while US hospitals are already overwhelmed.

A vaccine against fentanyl could stop the intense euphoria the drug creates and also block dangerous physiologic responses like respiratory depression, a new study suggests.

Early oseltamivir use reduced the length of hospitalization and risk for hospital readmission in children hospitalized with influenza, according to new research.

Confidence in vaccines is lower post-pandemic across all demographic groups and is not limited to traditional "anti-vaxxers," say authors of a new study.