April 28th 2025
Your daily dose of the clinical news you may have missed.
April 25th 2025
At current vaccination rates, measles could become endemic in the US again within 21 years; the threat extends to rubella, polio, and diphtheria, the study found.
April 17th 2025
The CDC advisory committee also endorsed GSK's pentavalent meningococcal vaccine.
April 15th 2025
Data from the EAGLE-1 study found gepotidacin to be noninferior to ceftriaxone plus azithromycin for treating uncomplicated urogenital gonorrhea.
April 9th 2025
AAAAI 2025: RSV vaccine and immunoprophylaxis uptake remained low in 2024 across infants, pregnant individuals, and older adults.
Cases and Conversations™: Applying Best Practices to Prevent Shingles in Your Practice
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Cedars-Sinai Study Said to Confirm Increased Risk of New-onset T2D After COVID-19 Infection
The EHR analysis found greater risk of type 2 diabetes after COVID regardless of vaccination status although odds were greater for those unvaccinated before infection.
It's Still Flu Season, Don't Let Patients Drop Their Guard, Says Expert
Medical director of the NFID William Schaffner, MD, shares his messages to primary care clinicians as the final months of this year's flu season near.
Changes to the ACIP 2023 Adult Immunization Schedule
Get a quick topline look at specific revisions and additions included in the ACIP's recommendations for routine immunization of those aged ≥19 years in the US.
One Office Visit, Multiple Vaccines: When is it OK?
Administering multiple vaccines at the same visit is shown to increase vaccination rates but is not always advisable. Try this quiz on 2 clinical scenarios.
Cash for Vaccination: Is it Effective? Is it Good Policy?
Lotteries with cash incentives and other giveaways are just one example of ways the COVID-19 pandemic changed the way US health care is handled.
Patients on the Vaccine Fence? Framing Vaccination as a Social Norm Can Help, Says Expert
Educating patients this flu season on prevention may not be sufficient to change their behavior. Framing vaccination as a social norm can help, says Dr William Schaffner.
Immunization Levels Disheartening This Flu Season, Says William Schaffner, MD
Vaccine uptake this respiratory virus season is lagging compared to previous years, says Schaffner, medical director of the National Foundation for Infectious Diseases.
COVID-19 Vaccines Safe and Effective in Children Aged 5-11 Years, According to New Research
Vaccination was associated with lower risks of infection, COVID-19-related illnesses, and hospitalizations due to COVID-19-related illnesses in children.
Long COVID in the US: By the Numbers
How many Americans report having long COVID symptoms? Which demographics is long COVID more prevalent in? A new analysis sheds light.
Respiratory Tripledemic 2022-23: Expert Update, Top Challenges
Distinguishing between influenza, COVID-19, and RSV and persuading vaccine-weary patients to get vaccinated are some of the challenges this season, says William Schaffner, MD.
FDA Advisory Committee Vote Unanimous on Harmonizing COVID Vaccine Formulations
The FDA and CDC must adopt the VRBPAC recommendation before it can be considered for implementation.
Evusheld EUA Withdrawn, FDA Recommends Other Therapies
The FDA wants clinicians to avoid using the neutralizing antibody as it appears to be less effective against newer circulating strains of the SARS-CoV-2 virus.
It's Vaccination Catch-up Time for Kids: An APB from AAFP President Iroku-Malize
AAFP president Tochi Iroku-Malize, MD, MPH, MBA, urges gentle but persistent efforts among all clinicians to get school-aged children back on vaccination track.
The COVID-19 Vaccine Halo Effect: Survey Highlights
The Kaiser Family Foundation survey found a 10% drop in the proportion of adults who say MMR vaccination should be required for school attendance, and other "halo" effects.
CDC Releases First Estimates of Bivalent mRNA COVID-19 Booster Effectiveness against XBB/XBB.1.5
Preliminary estimates showed relative bivalent booster dose vaccine effectiveness against XBB/XBB.1.5 for at least the first 3 months after vaccination.
Daily Dose: Most Long COVID Outcomes Resolve in 1 Year After Mild Infection
Your daily dose of clinical news you may have missed.
Moderna Reports Adult RSV Vaccine Efficacy of 84% in Phase 3 ConquerRSV Trial
The mRNA vaccine returned efficacy of 83.7% against RSV-associated lower respiratory tract disease defined by ≥2 symptoms and of 82.4% against disease defined by ≥3 symptoms.
Long COVID After Mild Infection: Most Symptoms Resolve After 1 Year, Finds Large Israeli Study
Overall dyspnea was the most common symptom of long COVID in the first year after infection, according to the nationwide retrospective cohort study.
Daily Dose: Universal DAA Therapy for all Persons with HCV
New Findings Underscore Need for Universal DAA Therapy for all Persons with Hepatitis C Virus Infection
Direct-acting antiviral treatment was independently associated with a lower risk of mortality and liver and nonliver outcomes in a large study of adults with chronic hepatitis C.
ACIP 2023 Vaccination Schedule Update, At-a-Glance
Among the CDC vaccine advisory group's recommendations are adding COVID-19 vaccines to the Vaccine for Children program and allowing PCV20 shots for those who previously received PCV13.
FDA Approves Novel Capsid Inhibitor for Super-Refractory HIV-1 Infection
Lenacapavir is the first of a new class of antiretrovirals, and it is indicated for persons with multidrug resistance, intolerance, or safety considerations.
Daily Dose: Bivalent Boosters Protect Against Severe COVID-19 Disease
CDC Real-world Studies Show Bivalent Boosters Protect Against Severe COVID-19 Disease
One study showed the boosters provide significant protection against hospitalization and ED care and the other found vaccine effectiveness of 84% in older adults.
She Treats Long COVID and Got it Herself: This Physiatrist Advocates for Federal Research and Patient Support
Physiatrist Monica Verduzco-Gutierrez, MD, highlights the state of long COVID management in the US and says primary care is crucial in diagnosing and treating the new condition.
COVID-19 Vaccines Have Saved 3 Million Lives in the 2 Years Since the First EUA
The vaccination campaign in the US also has prevented more than 18 million hospitalizations and saved $1 trillion in medical costs, according to a modeling study.
FDA Authorizes Bivalent COVID-19 Vaccines as Booster Dose in Children Aged 6 Months to 5 Years
The FDA amended Pfizer and Moderna EUAs for updated COVID-19 vaccines to include children as young as age 6 months as holidays and winter weather approach.
Daily Dose: Statin Prescribing in Primary Care
Influenza Update: Hospital Admissions Double During post-Thanksgiving Week
The inpatient flu census doubled after Thanksgiving travel and gatherings and ICU beds are full. More at-a-glance stats on Flu in the USA, here.
Seen in the ED: Elevated LFTs and Anemia in a Young Female Student
She reports cough and persistent escalating fever x2 weeks, headache but no neck stiffness. Tachycardia and mild skin pallor seen on PE. What do the lab tests tell you?