Friday's 5 Quotes for Primary Care - 4-7-2023
High salt intake linked to coronary atherosclerosis; daily ETOH, even in small doses, is dangerous; statins don't increase muscle injury; and 2 more studies of note.
6 Biologics for Severe Asthma, 3 Essential Facts on Each
For each of the 6 biologic agents FDA-approved for severe asthma, find the mechanism of action, indication, and biomarkers that predict enhanced response.
What, Exactly, is Alcohol Use Disorder?
AUD affects 15 million Americans, with men nearly 2 times more vulnerable to the disease vs women. Are you tracking signs and symptoms in your patients?
RSV Circulation Approximating Prepandemic Seasonality, Suggest New CDC Data
Onset of the 2022-2023 RSV season and its end were closer to historical patterns but atypical circulation may continue, say researchers writing in MMWR.
6 New Approved Drugs for Primary Care: Q1 2023
From type 2 diabetes to migraine, we have picked the top 6 FDA-approved drugs every primary care physician should know about from the first quarter.
What Does a Meningococcal Vaccine Have to do with an STI?
Vaccine side effects are usually trouble when they make the news. But sometimes, an unexpected result has merit. Find out more.
The Varicella Vaccine and Risk for Shingles: A 2-question Quiz
Universal vaccination against chickenpox with a live-attenuated varicella vaccine began 25 years ago. Were concerns about future shingles outbreaks borne out?
Seen in the ED: Facial Pain and Swelling, Sour Mouth
Pain and swelling have been present for 2 days, explains the patient, a man in his 50s. Other than mild tachycardia, vital signs are normal. What does the CT show?
Daily Dose: Safety, Efficacy of Analgesic Medicines for LBP Questioned
Your daily dose of clinical news you may have missed.
Respiratory Tripledemic 2022-23: An Expert Recap
William Schaffner, MD, medical director of the NFID, provides an expert recap of the 2022-2023 respiratory virus season for primary care clinicians.
Daily Alcohol Intake Appears More Dangerous than Not, Even in Small Doses and Particularly for Women
Results of previous studies supporting health benefits of low-dose, moderate drinking were likely skewed by bias and confounding, say authors of a new meta-analysis.
Cluster Headache, Migraine Show Strong Links to the Circadian System: Meta-analysis
Cluster headache and migraine are described as "highly circadian at multiple levels," suggesting hypothalamus involvement and potential for new treatments, study authors say.
Fibromyalgia May Predict Pain-related Worsening of Opioid Use Disorder, Say Authors of New Study
In a study of adults with pain in at least 1 body region, those with fibromyalgia had significantly greater odds of acknowledging pain-related addiction exacerbations.
Daily Dose: Multisite Chronic Pain & Risk for Dementia, Cognitive Decline
Sodium Intake Shows Strong Linear Relationship with Risk of Both Carotid and Coronary Atherosclerosis: Population-based Study
Each 1000 mg rise in Na excretion saw a corresponding 3%, 4%, and 4% higher risk of worsening carotid plaque, CAC score, and coronary artery stenosis, respectively.
Comparative Efficacy, Safety of Analgesics to Treat Acute Low Back Pain Questioned
Meta-analysis authors urge caution in use of analgesics used commonly to treat non-specific acute LBP in the absence of head-to-head RCT evaluating both efficacy and safety.
Daily Dose: Maternal Opioid Treatment Postpartum & Risk of Adverse Infant Outcomes
Multisite Chronic Pain Increases Dementia Risk, Hippocampal Injury: UK Biobank Analysis
The risk of neurocognitive abnormality increased with each additional pain site among patients with multisite chronic pain and appeared to be mediated by loss of hippocampal volume.
Moderate Exercise Does Not Increase Muscle Injury Markers in Statin Users who Are Symptomatic, Asymptomatic
Statin therapy did not exacerbate muscle injury, pain, or fatigue in persons engaging in moderate-intensity exercise, according to a new study.
FDA Requires Opioid Manufacturers to Provide Mail-back Envelopes to Accompany Prescriptions
Opioid manufacturers will supply outpatient pharmacies and other dispensers with pre-paid mail-back envelopes for disposal of unused medication.