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Bacterial meningitis and herpes simplex virus type 1 (HSV-1) encephalitis are both associated with significant morbidity and mortality. Thus, hospitalization and prompt initiation of therapy are essential.

While currently receiving chemotherapy with mitoxantrone for Gleason grade 7 prostate cancer, a 64-year-old man presented with rectal bleeding.

For several months, a 28-year-old man has had these changes to his nails, which have also become more brittle. He denies any history of trauma to the nails.

Be creative with performance rewards. Give movie tickets to employees who go “above and beyond” the call of duty.

Here is a tip that can help you cover all the elements of the review of systems: Ask the question as you examine the relevant body part.

Maintain a “murmur log” to record compliments and complaints from your patients.

Assign one clinical staff member to check the expiration dates on all prescription samples once a month, and keep a log of these inspections.

At sites where cosmesis is critical, such as on the face, use aluminum chloride and pressure for hemostasis rather than electrocautery.

I advise patients with diabetic neuropathy to break in new shoes gradually.

A 41-year-old woman presents to the emergency department with chest pain and dysphagia. Routine laboratory studies reveal profound neutropenia. She denies recent fever, chills, or weight loss.

Sandeep Juahar, who wrote an excellent warts-and-all account of his medical education in Intern: A Doctor’s Initiation, is now old enough to be having a midlife crisis. In a recent New York Times essay, he may or may not have been projecting his own current feelings of disillusion onto the entire medical profession. He writes about the sorry state of medical practice today.

In the next 5 minutes, Wilmer L. Sibbitt Jr, MD-one of the world's leading authorities on the subject-offers succinct answers to questions.

A Roster of HIV/AIDS-Related Resources

Biomarker:   Putative molecular indicator of a specific biological state.1  Some biomarkers, called surrogate endpoints, are used as substitutes for actual clinical endpoints such as incidence of disease or death.2

That’s the question we put to Dr. Kenneth Saag. In the next few minutes, Dr. Saag, will summarize the latest developments in osteoporosis therapy.

For 2 months, a 29-year-old man had pain and circular, soft swelling (7 x 7 cm in diameter) over the anterior left knee, superficial to the patellar ligament. Pain was minimal and associated with extension and flexion.

When counseling patients about why they should receive the influenza vaccine, I remind them that each year the disease kills 250,000 to 500,000 persons worldwide and more than 37,000 persons in the United States. This means that influenza kills more people per year than auto accidents.

Sometimes patients, particularly children and adolescents, are very anxious during the abdominal examination.