Alzheimer Disease/Dementia

Peanut butter and a ruler may turn out to be tools that offer an inexpensive, sensitive, and specific olfactory means of screening for Alzheimer disease. Details here.

The drive to screen older persons for minor memory changes is leading to unnecessary investigation and potentially harmful treatment, according to some experts.

As biomarkers to detect signals of Alzheimer disease improve at providing clinically meaningful information, a majority of Alzheimer researchers support disclosing results to research subjects who have these tests.

Researchers have devoted themselves to devising ways of blocking the production or accumulation of beta-amyloid. Now scientists are studying other protein targets, including tau.

If drugs could be developed to target tau, they might prevent much of the neurodegeneration that characterizes Alzheimer disease and help prevent or delay dementia.