Depression

SAN FRANCISCO -- Postmenopausal women with chronically elevated blood sugar had a nearly fourfold risk of mild cognitive impairment over four years compared with women with blood sugar in the normal range.

NEW YORK -- Severely depressed adults do not seem susceptible to an additional suicide risk from antidepressants as do children and adolescents, a case-control study here suggested.

BETHESDA, Md. -- Symptoms of depression can be made to disappear in less than two hours with a common anesthetic, not the weeks or months required for onset of relief with traditional antidepressants, according to results of a pilot study.

LONDON -- For some patients with cardiovascular disease risk factors, the root cause may be the loneliness of childhood, according to a study that followed more than 1,000 adults from birth.

STOCKHOLM -- Breastfeeding in infancy, even briefly, may help children later bounce back from stressful events like parental divorce.

NEW ORLEANS -- Combat soldiers returning from Iraq don't get over it quickly. Their neuropsychological adaptations to warfare are not easily set aside, according to a VA study reported here.

ABSTRACT: The number of medical therapies for patients with erectile dysfunction (ED) has increased in recent years because of our expanded understanding of the physiologic and neurologic causes of ED. Oral agents range from testosterone to antidepressants to phosphodiesterase inhibitors. Nitroglycerin and minoxidil have shown some effectiveness as topical agents. Alprostadil, which can be applied intraurethrally, is also effective as intracavernosal injection therapy. Prostaglandin E1 and papaverine are effective as intracavernosal injection agents. Some studies have shown that combined use of intracavernosal injection and oral therapy produces satisfactory erections.

ABSTRACT: The number of medical therapies for patients with erectile dysfunction (ED) has increased in recent years because of our expanded understanding of the physiologic and neurologic causes of ED. Oral agents range from testosterone to antidepressants to phosphodiesterase inhibitors. Nitroglycerin and minoxidil have shown some effectiveness as topical agents. Alprostadil, which can be applied intraurethrally, is also effective as intracavernosal injection therapy. Prostaglandin E1 and papaverine are effective as intracavernosal injection agents. Some studies have shown that combined use of intracavernosal injection and oral therapy produces satisfactory erections.

Primary care clinicians are encouraged to use the latest evidence-based diagnostic and therapeutic strategies from prospective randomized, controlled trials in their practice. But are the participants in these trials typical patients?

A succinct review of hyperkalemia . . . its various causes, clinical manifestations and consequences, ECG findings, and treatment approaches.

KINGSTON, Jamaica -- For growth-retarded children, an excess of play, talk, and toys can help avoid psychosocial hurdles in adolescence, according to a 16-year follow-up study.

VIENNA -- Carotid stenting can significantly ease both the frequency and severity of so-called "vascular depression," according to investigators here.

SAN FRANCISCO -- Unopposed transdermal estradiol at an ultra-low dose over two years did not affect cognitive function or health-related quality of life in post-menopausal women, researchers here reported.

BALTIMORE -- Forty years after the psychedelic drug culture proclaimed that psilocybin induces a profound mystical and spiritual experience, investigators at Johns Hopkins have agreed.

GAINSEVILLE, Fla. -- Apathy independent of depression may be a feature of Parkinson's disease for some patients, researchers here have found.

ADANA, Turkey - Illicit anabolic steroids may pump up athletes' gums as well as their muscles, according to periodontists here.

ASPEN, Colo. - Cardiologists suggested today that the sudden death here of Enron founder Kenneth Lay, 64, is a textbook example of catastrophic stress that can increase the risk of cardiac events.

Depression and obesity are often partners in pathology, according to investigators here.

abstract: There is increasing evidence that close monitoring and early intervention lead to better outcomes in patients with cystic fibrosis. At each office visit, spirometry should be performed and sputum culture specimens should be obtained; if the patient cannot produce sputum, a throat culture can be done instead. New respiratory symptoms or other evidence of worsening lung disease should prompt antibiotic therapy, increased airway clearance, and adjunctive anti-inflammatory medication as appropriate. Close attention should be paid to the patient's diet, appetite, stooling pattern, and growth measurements. Adolescents should be given additional information about their medications and adjunctive therapies to encourage them to take on a larger role in their own care. (J Respir Dis.2006;27(7):298-305)

A 68-year-old woman presents with recurrent nausea, vomiting, left upper quadrant pain, decreased appetite, and a 2.3-kg (5-lb) weight loss 1 month after she underwent selective splenic artery embolization for refractory thrombocytopenia secondary to hypersplenism.

Although the relationship is not completely understood, it is clear that anxiety and depression can adversely affect the course of asthma and chronic obstructive pulmonary disease.

ST. LOUIS PARK, Minn. - Constipation can trigger physical aggression in a nursing home resident with dementia, researchers here reported.

PRAGUE ? The evidence that led the FDA to warn that Paxil (paroxetine) taken during the first weeks of pregnancy increases the risk of birth defects, including serious heart defects, was disputed by German researchers today.

HOUSTON - Two drugs are waiting in the wings if Gleevec (imatinib) fails or is too toxic for patients with chronic myeloid leukemia (CML).

WASHINGTON - Lorcaserin, an investigational drug for the treatment of obesity, was successful at producing weight loss ranging between four and 7.9 pounds (1.8 to 3.6 kg) in a 12-week study, reported investigators here.