May 10th 2024
While Moderna expects mRNA-1345 to be approved later this month, the company cites FDA administrative constraints as reason for delay.
April 30th 2024
Your daily dose of the clinical news you may have missed.
April 22nd 2024
Researchers found that the COVID-19 booster dose elicited a 71%-84% increase in the median anti-spike half-life over that of the primary series.
March 29th 2024
Investigators found vaccine uptake of 41% among unvaccinated individuals who were part of a messaging intervention in the emergency department.
March 19th 2024
The novel 21-valent pneumococcal vaccine remains on track for the FDA PDUFA date of June 17, 2024; Merck adds this new data to the body of positive evidence.
Top 10 States Ranked by Percentage of COVID-19 Vaccines Given
COVID-19 vaccination progress based on proportion of vaccines administered is currently best in New Mexico and worst in Tennessee. Find out which states are in between.
Pfizer-BioNTech COVID-19 Vaccine Found Effective in Large, “Real World” Study
Results of a new study show that the Pfizer-BioNTech COVID-19 vaccine is 92% effective at preventing severe COVID-19 after 2 doses in over half a million study participants.
COVID-19 State Vaccination Priorities Change, As Needed
As states implement the CDC ACIP's COVID-19 vaccination priorities, they are revising them as needed based on federal, state, and local conditions. Here is a recent snapshot.
ACC Policy Statement: Prioritize COVID-19 Vaccine for Highest-risk CVD Patients
To ensure COVID-19 vaccination priority for the sickest CVD patients, the ACC statement identifies highest risk conditions within CVD to aid clinician decision making.
The COVID-19 Vaccine "Wait and See Group: Who are they?
As a group, Americans who want to wait and see how the COVID-19 vaccine works for others are younger and more diverse than those who want it ASAP.
COVID-19 Pandemic State Death Rates: Highest, Lowest
In the state with the highest COVID-19 death rate, 1 in every 406 residents has died; in the state with the lowest rate, the number is 1 in every 3436. Which states are they?
COVID-19 Updates: US and Global Cases, Deaths, and Recoveries as of February 8, 2021
Global confirmed cases of COVID-19 have surpassed 106 million. We summarize more of today's data from the Johns Hopkins COVID-19 interactive map.
Racial Disparities in COVID-19 Vaccination: Data from 23 States
Kaiser Family Foundation: New data from 23 states show consistently smaller shares of vaccination among Blacks vs Whites based on share of cases and deaths and of total population.
Pfizer, Oxford-AstraZeneca Vaccines to be Studied in Alternating Doses
Oxford researchers will evaluate the interchangeability of the vaccines, the impact of different dosing intervals, and the potential for enhanced immune response.
Patients Often Miss Boosters in 2-dose Vaccine Regimens
Patients most often blame forgetfulness for not getting a second shot so reminders are key; just don't rely on a message via a patient portal to reach them.
Novavax, J&J Vaccine Candidates Effective Against COVID-19, Variants
Vaccines from both companies were significantly effective against COVID-19 and show promise against variants from the UK and South Africa.
COVID-19 Vaccine: US Cities in Greatest Immediate Need
Availability of the COVID-19 vaccine cannot come fast enough for many large US cities, based on the share in each of the most vulnerable populations.
FDA Update: Blood Donation During COVID-19 Pandemic
The FDA provides details on how COVID-19 infection or vaccination against the virus affects a waiting period to donate. Please share the information with your patients.
7 Myths and Facts about the COVID-19 Vaccines for PCPs and Patients
Patients trust primary care providers for accurate information on the COVID-19 vaccines. Here are 7 of the many myths now widespread you may need to explain to your patients.
PCP Survey Finds Patient Vaccine Distrust High, Health Issues More Complex
A majority of primary care clinicians report their patients worry about COVID-19 vaccine side effects and the speed of vaccine development. Most do plan to be vaccinated themselves.
The View from One Hospital's COVID-19 Trenches
The bad news, writes ID expert and AIDS researcher Rodger MacArthur, MD, is the New Year's surge in his hospital's COVID-19 cases. The good news? Vaccines.
J&J COVID-19 Single-dose Vaccine Candidate Shows Promise
Johnson & Johnson single-dose COVID-19 vaccine candidate induces durable immune response in participants aged 18 to 55 years; results support further development.
The COVID-19 Variants: What We Know So Far
What are the implications of the global emergence of SARS-CoV-2 variants in terms of disease severity and vaccine and treatment efficacy?
COVID-19: ACP Releases Statement on Vaccine Provision, Payment
Recommendations address the role of clinicians as vaccinators and stress as essential communication and collaboration with patients' primary care team.
Pfizer & Moderna COVID-19 Vaccines: Side-by-side Comparison
The 2 FDA-approved COVID-19 vaccines are similarly effective but also very different in a number of ways that will affect distribution.
Trust in the COVID-19 Vaccine is Fluid: KFF Vaccine Monitor Project Explains
A new Kaiser Family Foundation survey project found 85% of respondents trust their regular healthcare provider for information COVID-19 vaccination. PCPs, read more.
How to Manage Post-COVID-19 Vaccination Reactions among Healthcare Staff
Vaccination against COVID-19 for US healthcare personnel began on December 14, 2020; the same day, CDC hosted a webinar on how to ensure HCP health and safety during this period.
State COVID-19 Vaccine Distribution Plans, Priorities
Early COVID-19 vaccine demand will far exceed supply and so states have been refining distribution plans for months. Here is a topline review of what to expect.
6 Essential COVID-19 Codes to Remember
COVID-19 cases are surging across the country as the US heads into holiday season. Counsel patients on staying safe and keep these billing codes very close at hand.
Moderna COVID-19 Vaccine Candidate Achieves 94.5% Efficacy in Phase 3 Trial
Moderna announced safety and efficacy data from the phase 3 COVE trial that found mRNA-1273 94.5% effective in preventing infection with SARS-CoV-2.
NIH Updates Testing, Treatment Guidelines During Cocirculation of Influenza and COVID-19
The new guideline section stresses that testing is the only way to accurately discriminate between the 2 viruses and advises on influenza vaccination and treatment.
FDA Issues EUA Guidance for COVID-19 Vaccines
The FDA has issued guidance for sponsors of requests for EUA for COVID-19 vaccines including details on clinical trial data required to support award of EUA.
COVID-19 Vaccine: Pharmaceutical Executives Pledge Safety Above All
CEOs of 9 drug companies involved in COVID-19 vaccine development signed a pledge ensuring that sound science and ethics will guide the process.
3 Influenza Season Imperatives: Vaccinate, Vaccinate, Vaccinate
The CDC estimates delivery of a record 194 to 198 million doses of influenza vaccine this year. The primary care imperative: vaccinate, vaccinate, vaccinate.
Phase 3 Trials Launched for AZ SARS-CoV2 Vaccine Candidate
The AstraZeneca-Oxford University investigational coronavirus disease 2019 (COVID-19) vaccine candidate, has expanded into a phase 3 clinical trial.