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The FDA's ODD award is based on the positive findings from the phase 2 TouCAHn trial, which also support Crinetics' robust phase 3 pivotal clinical trial program for the novel agent.

Vaginal estradiol is often prescribed as first-line therapy for genitourinary syndrome of menopause, making the findings supportive of current clinical practice.

A Cleveland Clinic trial revealed that AI-driven precision treatment significantly reduced HbA1c and body weight, often eliminating need for medications other than metformin.

Your daily dose of the clinical news you may have missed.

The risk for MDD is greatest in the first month after diagnosis and the absolute risk remains elevated even 20 years later, making early detection and treatment imperative.

The first oral penem antibiotic, Orlynvah™, has launched in the US, offering a vital treatment option for women with resistant uncomplicated UTIs.

This week’s roundup covers nutrition counseling barriers, tau pathology in mood disorders, RSV protection, AD patient needs, and a new Shingrix syringe.

William Schaffner, MD, advises first and foremost to stay away from politics, to acknowledge and normalize patient fear and concern, and to answer quickly and with confidence.

A recent study showed obesity in childhood or adolescence accelerates biological aging by up to 48% in young adults.

In its updated guidelines, the AAP recommends that all children aged 6 to 23 months be vaccinated against COVID-19, citing the population's high risk for severe infection.

Your daily dose of the clinical news you may have missed.

Sarah Sams, MD, emphasizes education, empathy, and proactive communication to support families and protect public health.

Risk of dementia was more than 60% lower among adults aged 60 to 69 years with hearing loss who used hearing aids in the first study to highlight early intervention.

William Schaffner, MD, ID specialist and vaccine expert, advises following state guidance on back-to-school shots and thinking through new guidance on COVID shots for kids.

New data show more than one-third of US adults are unaware of HPV or the HPV vaccine, with gaps greatest in the Midwest and South, where HPV-related cancers are most common.

The GLP-1/GIP receptor agonist also showed promise in an exploratory maintenance arm, producing rapid weight loss at an induction dose that was sustained after down-titration.

Your daily dose of the clinical news you may have missed.

Infectious disease expert Amesh Adalja, MD, discusses new vaccine policies, misinformation, and how PCPs can build confidence during National Immunization Awareness Month.