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A new report shows that persons with HIV/AIDS and transplant patients are much more likely to contract about 20 different cancers than those in the general population (McLean T. Australian Associated Press. June 6, 2007). Conducted by the University of New South Wales, the study found that immune deficiency-a problem common to the 2 groups-makes them more vulnerable to infections and cancers, including those in the liver, stomach, skin, lung, cervix, eye, lip, mouth, and penis.

A 22-year-old man with a history of AIDS, gastritis, and perianal warts presented to his primary care physician with a complaint of worsening dyspepsia and diarrhea.

Lichen myxedematosus, or papular mucinosis, is a skin disorder characterized by accumulation of mucin in the dermis. We present the case of a patient with HIV infection and lichen myxedematosus whose skin condition completely resolved with antiretroviral therapy. [AIDS Reader. 2007;17:418-420]

ROCKVILLE, Md. -- Although there was an overall drop in childhood death rates from all causes from 1969 through 2000, most of the declines occurred among children from upper income brackets.

SEATTLE -- Newborn hearing tests may provide a marker for infants at risk for sudden infant death syndrome (SIDS), researchers found.

A 77-year-old man complains of deep, aching pain of several months' duration in his left thigh that is exacerbated by both standing and walking.

Drugs may confer serious risks along with substantial therapeutic benefits. The aging of the population and the trend toward increased outpatient drug use-and hence the likely rise in adverse events-underscore the need for ongoing surveillance of outpatient drug safety.

When you palpate for inguinal hernias, ask the patient to take a deep breath and then bear down in a moderately strenuous Valsalva maneuver--rather than cough--after you have placed your finger in the inguinal ring.

ABSTRACT: Angiotensin-converting enzyme inhibitors and ß-blockers are the cornerstone of heart failure medical therapy; unless contraindicated, start these agents as soon as possible after volume status has been optimized. Aldosterone receptor antagonists, angiotensin-receptor blockers, and a fixed-dose combination of hydralazine and isosorbide dinitrate (the last recommended especially for African Americans) can be used as add-on therapy. Prophylactic implantable cardioverter defibrillators reduce long-term mortality in symptomatic patients with a left ventricular ejection fraction (LVEF) of 35% or less. Cardiac resynchronization therapy improves symptoms and ventricular remodeling in some patients; indications include wide (more than 20 milliseconds) QRS complex on ECG, impaired LVEF (35% or less), and advanced heart failure symptoms (NYHA classes III and IV) despite optimal drug therapy. Measurement of natriuretic peptides and impedance cardiography both show promise for monitoring patients with heart failure and for guiding therapy, but definitive data to justify their routine use are still lacking.

Oral Histoplasmosis

A 39-year-old woman complained of excruciating pain that radiated from a chronic lesion on the left upper lip to the entire left side of the face. She had AIDS but was not receiving antiretroviral therapy.

In the late 1980s, "club drugs" were typically limited to the so-called rave/techno subculture.1 More recently, studies have shown the growing appeal of 3,4-methylenedioxymethamphetamine (MDMA), or ecstasy to middle-aged and older adults.