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ROCHESTER, Minn. -- For smoldering multiple myeloma, the risk of progression to active disease may be predicted by a pair of factors at diagnosis, according to researchers here.

SEATTLE -- When estimating left ventricular filling pressure to assess cardiac risk, physicians can choose clinical or echocardiographic criteria, depending on whether they want sensitivity or specificity.

ST. LOUIS -- Women who got most of their calcium from food had higher bone-mineral densities than patients who relied on supplements, researchers here reported.

SEATTLE -- Preclinical atherosclerosis, often missed by conventional risk assessment, can be broadly identified by vascular ultrasound, investigators said here.

UPPSALA, Sweden -- Osteoporotic fracture may be less common among men than women, but a lifetime of physical activity appears to be just as important in reducing this risk, researchers found.

DUARTE, Calif. -- In the face of early-onset breast cancer, too few women in the family can taint the potential accuracy of models to determine the need for full-blown BRCA testing.

INDIANAPOLIS -- Infants and toddlers are the children most likely to be injured in elevator accidents, reported investigators here. Soft-tissue injuries to upper extremities are the most common trauma types.

BARCELONA, Spain -- Ofatumumab (HuMax-CD20), an investigational fully human antibody, appears to be safe and effective for rheumatoid arthritis, researchers said here.

REYKJAVIK, Iceland -- There's more evidence that mutations in the BRCA2 cancer susceptibility gene can contribute to prostate neoplasia as well as to breast and ovarian malignancies.

MINNEAPOLIS, Minn. -- When arthritis patients took extended release morphine sulfate (Avinza) on awakening, they got to sleep more easily at night and slept better and longer, researchers found.

BERKELEY, Calif. -- Arsenic exposure increases the risks of bladder and lung cancer starting a decade after chronic exposure, researchers here reported.

INDIANAPOLIS -- Authorizing emergency department physicians to send ST-elevation myocardial infarction (STEMI) patients directly to the cath lab resulted in 71% being treated within 90 minutes of symptom onset.

PITTSBURGH -- A new mathematical model of sepsis may help physicians make better clinical decisions, researchers here hope.

SANTA MONICA, Calif. -- The higher the number of chronic medical problems patients have, the better the quality of their healthcare tends to be, a finding that should reassure quality-of-care watchdogs.

CHICAGO -- Most intracranial arterial aneurysms in children appear to arise spontaneously in the anterior circulation, and not, as commonly believed, as a result of trauma, infections, or vascular malformations, reported investigators here.

WASHINGTON, D.C. -- The odds of getting an NIH grant are a lot better for Ph.D.s and M.D.s who also hold a Ph.D. than for physicians who have a medical degree alone, one study showed.

CINCINNATI -- For treating the chronic pain and other symptoms of fibromyalgia, the anticonvulsant gabapentin (Neurontin) proved safe and effective, researchers here reported.

VIENNA -- Three drugs, two approved and one in the pipeline, are improving care for patients with severe rheumatoid arthritis (RA), according to clinicians here.