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LYON, France -- When multiple sclerosis (MS) strikes in childhood, it develops more slowly than adult-onset disease, but still leads to irreversible disability at a younger age, researchers here found.

WASHINGTON -- Most of the nearly 800 brands of sunscreen on the U.S. market either fall short of their claims or contain unsafe ingredients, according to an environmental watchdog group here.

ROCHESTER, Minn. -- For smoldering multiple myeloma, the risk of progression to active disease may be predicted by a pair of factors at diagnosis, according to researchers here.

SEATTLE -- When estimating left ventricular filling pressure to assess cardiac risk, physicians can choose clinical or echocardiographic criteria, depending on whether they want sensitivity or specificity.

ST. LOUIS -- Women who got most of their calcium from food had higher bone-mineral densities than patients who relied on supplements, researchers here reported.

SEATTLE -- Preclinical atherosclerosis, often missed by conventional risk assessment, can be broadly identified by vascular ultrasound, investigators said here.

UPPSALA, Sweden -- Osteoporotic fracture may be less common among men than women, but a lifetime of physical activity appears to be just as important in reducing this risk, researchers found.

DUARTE, Calif. -- In the face of early-onset breast cancer, too few women in the family can taint the potential accuracy of models to determine the need for full-blown BRCA testing.

INDIANAPOLIS -- Infants and toddlers are the children most likely to be injured in elevator accidents, reported investigators here. Soft-tissue injuries to upper extremities are the most common trauma types.

REYKJAVIK, Iceland -- There's more evidence that mutations in the BRCA2 cancer susceptibility gene can contribute to prostate neoplasia as well as to breast and ovarian malignancies.

BARCELONA, Spain -- Rheumatoid arthritis responds more quickly to certolizumab pegol (Cimzia) than to other tumor necrosis factor-a inhibitors, researchers have found.

MINNEAPOLIS, Minn. -- When arthritis patients took extended release morphine sulfate (Avinza) on awakening, they got to sleep more easily at night and slept better and longer, researchers found.

BERKELEY, Calif. -- Arsenic exposure increases the risks of bladder and lung cancer starting a decade after chronic exposure, researchers here reported.

INDIANAPOLIS -- Authorizing emergency department physicians to send ST-elevation myocardial infarction (STEMI) patients directly to the cath lab resulted in 71% being treated within 90 minutes of symptom onset.

PITTSBURGH -- A new mathematical model of sepsis may help physicians make better clinical decisions, researchers here hope.

SANTA MONICA, Calif. -- The higher the number of chronic medical problems patients have, the better the quality of their healthcare tends to be, a finding that should reassure quality-of-care watchdogs.

CHICAGO -- Most intracranial arterial aneurysms in children appear to arise spontaneously in the anterior circulation, and not, as commonly believed, as a result of trauma, infections, or vascular malformations, reported investigators here.

WASHINGTON, D.C. -- The odds of getting an NIH grant are a lot better for Ph.D.s and M.D.s who also hold a Ph.D. than for physicians who have a medical degree alone, one study showed.