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ANN ARBOR, Mich. -- Fatter, poorer, and less educated breast cancer patients are more likely to get partial-dose chemotherapy, which may jeopardize their survival, researchers reported.

ORLANDO -- A genetic signature related to telomerase has been strongly associated with an increased risk of death in patients with gastrointestinal stromal tumors (GIST), researchers reported here.

ORLANDO -- About half the patients with resectable stomach cancer who would benefit from adjuvant chemoradiation do not get it, researchers reported here today.

WAGENINGEN, The Netherlands -- Folic acid supplementation, improves cognitive function, particularly memory, among older adults with poor folate status, according to Dutch researchers.

ANN ARBOR, Mich. -- The clinical outcome of breast cancer and three other tumor types can be deduced by a "genetic signature" made up of 186 genes, according to researchers here.

EINDHOVEN, The Netherlands -- First-generation stent grafts for endovascular repair of abdominal aortic aneurysms (AAA), used only in Europe, have a high rate of rupture and other early and late complications, reported European physician.

NEW HAVEN, Conn. -- Although opioids may give patients with chronic back pain temporary relief, the drugs' long-term efficacy is uncertain, and they carry a high potential for abuse, found a systematic review of clinical studies.

PHILADELPHIA -- The FDA has approved a once-daily formulation of Lialda (mesalamine) for active mild-to-moderate ulcerative colitis, Shire PLC announced.

CAMBRIDGE, England -- Defects in the receptor for leptin are rare but should be considered when diagnosing obese patients with uncontrolled appetites, according to researchers here.

WATERTOWN, Mass. -- Instead of popping pills, men with erectile dysfunction may be able to improve their performance through weight loss and getting in shape.

BOSTON -- The fallout of New York State's rules discriminating against benzodiazepine prescriptions for older Medicaid patients was a nearly two-thirds drop in their use but no reduction in hip fracture rates, reported Harvard researchers.

BOSTON -- Smokers run a higher risk than non-smokers of having latent or active tuberculosis and of dying from the disease, according to researchers here.

LEEDS, England -- Increasing the intensity of chemotherapy for osteosarcoma of an extremity does not improve overall or progression-free survival despite improvements in histologic response, according to a large European trial.

ROYAL OAK, Mich. -- Citing "catastrophic complications" if dual-antiplatelet therapy is halted during the 12 months after implanting a drug-eluting stent, five professional societies signed off on a stern advisory aimed at reducing the risk of thromboses.

TORONTO -- The analytic method used to correct for selection bias in observational studies can mean the difference between a 50% treatment effect and a 16% treatment effect, researchers here reported.

BERLIN, Germany -- After complete resection of pancreatic tumors, chemotherapy with Gemzar (gemcitabine), which is FDA-approved for locally advanced or metastatic malignancies, significantly delayed disease recurrence, researchers here reported.

BOSTON -- Men with periodontitis and tooth loss, or both, had an overall 64% greater risk of cancer of the pancreas than men with good oral health, according to data from Health Professionals Follow-up Study.

BOSTON -- An investigational drug aimed at making recurrent glioblastomas more vulnerable to chemotherapy and radiation seems to restore a normal vasculature to the tumor, at least temporarily, show preliminary results of a Phase II trial.