BOSTON -- Women whose mothers took the synthetic estrogen DES (diethylstilbestrol) have a sharply increased risk of breast cancer once they are 40 or older, according to researchers here.

NEW YORK -- The summer is barely half over, and much of the country has had enough-enough of heat-related illness, enough heat-related power outages, and enough heat-related misery from a sweltering wave of extraordinary heat that broke records from coast to coast.

SAN FRANCISCO -- Women with a strong genetic predisposition to rheumatoid arthritis aren't exacerbating the problem by smoking, surprised investigators here discovered.

SAN FRANCISCO -- Even though anticoagulation for atrial fibrillation may boost the chance of an intracranial bleed slightly in older patients, the benefits of the therapy outweigh the risk of a hemorrhage, according to researchers here.

NEW YORK -- Paternal age is a significant risk factor for miscarriage, according to a case control study of almost 14,000 pregnancies. It showed that men start to go downhill after 35.

PAMPLONA, Spain -- Severe obstructive sleep apnea more than doubled the risk of a first ischemic stroke in persons over age 70, researchers here reported.

BALTIMORE -- Chemicals in curry and onions may put the heat on colorectal cancer, helping to reduce both the size and number of adenomas in patients genetically prone to them.

TORONTO -- Most out-of-hospital cardiac arrests end on the scene, and investigators here have devised a simple clinical prediction rule to help emergency workers know when to stop.

CHICAGO -- High blood pressure appears to impair older patients' ability to walk, and the reason may be more than just peripheral arterial disease.

MAINZ, Germany -- The success of chemoembolization tumor debulking is a better indicator of which liver cancer patients will do well with a transplant than the current standard of size and number of lesions, according to investigators here.

HAMILTON, Ontario -- When women are screened for domestic violence, they'd rather have it done via a private questionnaire than in a face-to-face interview, investigators here found.

ORLANDO -- A mixture of radiation beams -- carefully planned using a sophisticated computer modeling system -- can reduce the dose needed to treat breast tumors, researchers reported here.

BOSTON -- Decreasing tuberculosis treatment to two months from six months and improving case detection would theoretically double or triple the expected decline in TB incidence and mortality, according to a mathematical model.

Smoking cessation programs have been recognized to benefit from standard clinician intervention and telephone counseling, but what are the comparative benefits of these strategies? Researchers examining the relative benefits of telephone care and clinician intervention found that telephone care leads to higher smoking cessation rates.

ABSTRACT: The number of medical therapies for patients with erectile dysfunction (ED) has increased in recent years because of our expanded understanding of the physiologic and neurologic causes of ED. Oral agents range from testosterone to antidepressants to phosphodiesterase inhibitors. Nitroglycerin and minoxidil have shown some effectiveness as topical agents. Alprostadil, which can be applied intraurethrally, is also effective as intracavernosal injection therapy. Prostaglandin E1 and papaverine are effective as intracavernosal injection agents. Some studies have shown that combined use of intracavernosal injection and oral therapy produces satisfactory erections.

ABSTRACT: The number of medical therapies for patients with erectile dysfunction (ED) has increased in recent years because of our expanded understanding of the physiologic and neurologic causes of ED. Oral agents range from testosterone to antidepressants to phosphodiesterase inhibitors. Nitroglycerin and minoxidil have shown some effectiveness as topical agents. Alprostadil, which can be applied intraurethrally, is also effective as intracavernosal injection therapy. Prostaglandin E1 and papaverine are effective as intracavernosal injection agents. Some studies have shown that combined use of intracavernosal injection and oral therapy produces satisfactory erections.

A 16-year-old boy complains of right lower leg pain that began after his first week at a summer basketball conditioning camp. Before he left for the camp, he was jogging off and on, averaging a few miles a week.

Basal cell carcinoma (BCC) is the most common cancer in the United States; more than 1 million cases are reported annually. BCC is a carcinoma of aging and usually manifests in areas of chronic sun exposure.

With the advent of minimally invasive therapies and new anesthesia techniques, chronic venous disease can now be treated cost-effectively in an office setting.

These hyperkeratotic, hemorrhagic, depressed ulcerations developed on the feet of a 45-year-old white man with a 4-year history of systemic lupus erythematosus (SLE).