For 20 months, a 23-year-old woman had bone pain that traveled to all of her extremities and was unrelated to physical activity. Physical findings were normal. An isolated increase in the serum calcium level was noted. Radiographs of the left and right femurs revealed diffuse diaphyseal thickening. A nuclear medicine bone scan demonstrated increased activity in the diaphyseal regions of the long bones, with a slight increase in cranial uptake.
A review of the environmental determinants of allergic rhinitis and asthma, including house dust mites, cats, dogs, and cockroaches.
Avoidance of allergens and irritants known to cause or aggravate allergic rhinitis and asthma is a key component in the management of these disorders.
BETHESDA, Md. - Inherited variations in a gene that codes for skin pigmentation can dramatically increase the risk of acquiring mutations in another gene that's linked to one form of melanoma, according to researchers here.
ST. LOUIS PARK, Minn. - Constipation can trigger physical aggression in a nursing home resident with dementia, researchers here reported.
DALLAS ? The 30-minute time frame for beginning a cesarean after the decision is made for one should be the suggestion it was intended to be and not the rule it has become, researchers here said.
SEATTLE - Blind drunk is much more than a vivid description of big-time intoxication, according to investigators here. It is also a state of visual inattention while driving that may not take much alcohol to attain.
ROCKVILLE, Md. - The FDA today granted accelerated approval to Sprycel (dasatinib) for adults with chronic myeloid leukemia who are intolerant to Gleevec (imatinib) or become resistant to it.
EDINBURGH - A new set of clinical criteria-embodied in a Web-based tool-improves the ability of oncologists to diagnose patients with Lynch syndrome, according to Scottish researchers.
BALTIMORE ? Don't let the bedbug's bite go misdiagnosed, pediatric dermatologists here advise. A simple set of diagnostic principles may help to determine whether a child's rash comes from bedbug or flea bites, or something else.
DENVER - Treatment decisions for localized prostate cancer tend to be driven more by patients' fears and misconceptions rather than by understanding of the evidence, according to accounts of newly diagnosed patients.
NEW YORK - Blood that has been awaiting use in a hospital for several weeks has been associated with a higher risk of complications in patients undergoing repeat cardiac surgery.
NEW HAVEN, Conn. - Preserved placentas from children later diagnosed with autism contained cellular abnormalities that could be the earliest signs of the condition.
PARIS ? Diagnostic chest x-rays apparently bestow an increased risk of breast-cancer in women with mutations in BRCA susceptibility genes.
ROME - Cell phone signals alter the excitability of the nearby motor cortex, according to researchers here, who don't know what the finding means, if anything.
PRAGUE, Czech Republic - Many women awaiting in-vitro fertilization (IVF) would prefer to have a child with cerebral palsy or other birth defects rather than have no child at all, according to a study presented here.
AMSTERDAM ? Two-year data from the extension of a major trial of Orencia (abatacept) suggest that the agent continued to prevent the advance of structural damage in rheumatoid arthritis, researchers reported here.
ATLANTA - Six unrelated clusters of community-acquired methicillin-resistant Staphylococcus aureus infection involving 44 people in three states have been linked to 13 unlicensed street-corner tattoo artists.
GALVESTON, Tex. - Whether a man with prostate cancer is treated with androgen deprivation may depend more on his choice of urologist than on the nature of his tumor or his age, researchers here suggested.
LOS ANGELES - The alkylating chemotherapy agent Cytoxan (cylcophosphamide) can produce small but significant improvements in lung function in patients with scleroderma, but its toxicities must be weighed against its potential benefits.