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BOSTON -- Elderly male smokers have nearly twice the risk of age-related macular degeneration as their elderly brethren who don't smoke, according to researchers here. But eating two or more servings of fish a week sharply reduced the risk.

TORONTO -- Women with harmful mutations in the two major susceptibility genes linked to breast cancer can sharply reduce their risk of an ovarian malignancy by having their ovaries and fallopian tubes resected, according to researchers here.

VALENCIA, Spain -- With a combination of pegylated interferon and Rebetol (ribavirin), liver transplant recipients with recurrent hepatitis C (HCV) infection respond as well as non-transplants patients, researchers here reported.

LOS ANGELES - Throughout the genome, males and females express the same genes differently, a finding that may help explain well-established differences in how men and women respond to medical treatment.

Abstract: Elderly persons with active tuberculosis may present with the classic features, such as cough, hemoptysis, and fever, but some patients present with less typical signs, such as hepatosplenomegaly, liver function abnormalities, and anemia. A high index of suspicion is required when a patient presents with cough or pneumonia unresponsive to conventional therapy. Acid-fast smear and mycobacterial culture of a sputum specimen are recommended for diagnosis. For an elderly patient who tests positive with purified protein derivative, 9 months of isoniazid prophylaxis is recommended. For patients who are intolerant of isoniazid or have been exposed to or infected by an isoniazid-resistant strain, rifampin single-agent preventive therapy may be an effective alternative. (J Respir Dis. 2006;27(7):307-315)