Beyond Vasomotor Symptoms: The Potential Role of NK Receptor Antagonism in Mood and Sleep

The conversation examines how NK pathways influence not only temperature control but also mood and circadian rhythm regulation. By stabilizing neurochemical communication, NK antagonists may indirectly alleviate menopausal anxiety, irritability, and sleep disturbance.

Panelists emphasize the interconnection between vasomotor symptoms, sleep, and mental health, noting that effective thermoregulation often leads to downstream emotional benefits. Improved sleep architecture translates into better daytime function and emotional resilience.

This segment highlights NK receptor antagonism as a multidimensional tool that addresses both physiological and psychosocial aspects of menopause.