Depression

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BOSTON -- Suicidal tendencies that arise in some men who start on the antidepressant citalopram (Celexa) may be linked to genetic mutations, investigators in Boston and Dallas reported.

I am an adult psychiatric nurse practitioner, and a significant part of my practice has been the treatment of subclinical hypothyroidism. Whenever a patient has depression and low energy, I measure free T4, free T3, and thyroid-stimulating hormone (TSH) levels. In most of the subclinical hypothyroidism I have detected, the TSH level is normal. In many cases, the only level that is low is the free T3. When liothyronine is prescribed for these patients, their symptoms of depression and tiredness decrease and their need for antidepressants has, in a few cases, been eliminated.

PHILADELPHIA -- The most obvious clinical feature of obstructive sleep apnea may be weariness of mind, but this breathing disorder also slowly and silently wears down the heart, according to researchers.

SAN DIEGO -- Aripiprazole (Abilify) may be a useful adjunctive therapy in patients with major depressive disorders who have incomplete responses to antidepressants, researchers reported here.

DRESDEN, Germany -- Treating Parkinson's disease patients with the antioxidant coenzyme (CoQ10) boosts plasma levels of the substance but doesn't improve disease symptoms, reported investigators here.

WASHINGTON -- An employee health program incorporating a fitness center, health education, and incentives improved workers' cardiovascular health and workplace safety, investigators reported here.