March 24th 2023
Statin-eligible patients in minority groups significantly undertreated; metabolically healthy obesity on the rise; menstruation irregularities suggest later CVD risk; and 2 more studies of note.
November 1st 2021
May 19th 2016
July 30th 2015
While it might be tempting to dismiss this as a picker's nodule, lesion's thickness suggested the need for a biopsy, which revealed that the lesion was an infiltrative, invasive basal cell carcinoma. The lesson? Never hesitate to biopsy when the slightest uncertainty exists as to the correct diagnosis.
The predominantly infraorbital erythema and swelling suggested that this rash was related to a material that was being placed in the eyes and dripping from them. Patch testing showed that the patient was allergic to the preservative in the eyedrops she had been using.
Proliferating Actinic KeratosisMarch 7th 2013
The redness on this woman's nose represents fairly severe photodamage with extensive actinic keratosis. Use of a topical therapy to achieve clearance of a field of actinic damage can be done with imiquimod, 5-fluorouracil, or ingenol mebutate creams, or diclofenac gel.
Cutaneous Horn Arising From a Seborrheic KeratosisFebruary 23rd 2013
Cutaneous horns can arise on top of: seborrheic keratosis (as in this patient’s case), actinic keratoses, warts, basal and squamous cell carcinomas. Therefore, the lesion-and especially the base-must be submitted for pathologic diagnosis.
Fixed Drug Eruption Caused by DoxycyclineFebruary 6th 2013
The morphology of a round, red to purple patch, with or without blistering, is typical of a fixed drug eruption. This entity usually manifests as a solitary spot, but can be multiple. Tetracycline antibiotics and barbiturate sedatives are common causes. This patient had been taking doxycycline.
Condylomata Acuminata (Severe External Genital Warts)January 28th 2013
Condylomata acuminata this extensive are beyond the capacity of all topical therapies. The area was initially treated by carbon dioxide laser ablation, and residual small foci of infection were subsequently treated with topical 5% imiquimod cream.
The combination of itching massive scaling suggests the diagnosis of crusted scabies. This variety of scabies is seen in those who are immunosuppressed or immunocompromised (typically HIV+). Repeated oral doses of ivermectin along with topical permethrin application were required to clear this infestation.
This multi-factorial eruption requires topical or systemic antifungal treatment in conjunction with broad-spectrum antibacterial therapy, topical desiccating maneuvers (such as Burrow’s soaks), and discontinuation of OTC interventions that might be worsening the problem.
Squamous Cell Carcinoma of the PenisDecember 5th 2012
There is a rather large erythematous patch/plaque present. However, an exophytic, verrucous nodule is visible at the inferior border of the tumor. Biopsy of the flatter portion of this lesion disclosed squamous cell carcinoma in-situ, while biopsy of the nodule revealed invasive squamous cell carcinoma.
Post-traumatic Subcutaneous HematomaNovember 9th 2012
This large bruise developed after the patient had an accident in her yard. Post-traumatic subcutaneous hematomas are common in elderly women, especially those who are anticoagulated. Untreated, the hematoma can eventuate into an abscess and even sepsis.
Malignant Melanoma on a Patient’s BackOctober 23rd 2012
The only impressive thing about this lesion was a “notch” in its superior pole, and some mild pigment heterogeneity. Prudent caution proved extremely beneficial. The history of a “new” lesion in a patient with almost no visible nevi, along with some very subtle gross features, led to early recognition and elimination of a malignant melanoma.