Infectious Disease

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I have recently seen several patients who were treated for infections by emergency department physicians and who were given oral corticosteroids along with antibiotics. My understanding of the action of corticosteroids is that they suppress the immune system. If this is true, why would they be given to someone who already has an infection?---

An 89-year-old woman, who has long lived on the special care (dementia) unit of a nursing home because of advanced Alzheimer disease, is seen to assess possible injuries after a fall. Many prior falls have been ascribed to her lack of safety awareness in negotiating the environment, rather than to neuromuscular, sensory, or cerebellar deficits.

SAN FRANCISCO -- The antibiotic Tygacil (tigecycline) is highly effective against multidrug resistant strains of acinetobacter, which are an increasing problem in intensive care units, researchers reported here.

SAN FRANCISCO -- Even with appropriate antibiotics, methicillin-resistant Staphylococcus aureus (MRSA) infections relapse about 25% of the time, researchers reported here. And for MRSA-related osteomyelitis, there is a 46% relapse rate.

ICAAC: Pigs Add New MRSA Woe

SAN FRANCISCO -- A porcine wrinkle has emerged in the struggle against community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) in The Netherlands, researchers recounted here.

HOUSTON -- Children with acute bacterial infections of skeletal muscle caused by methicillin-resistant Staphylococcus aureus (MRSA) strains are showing up with increasing frequency in pediatric clinics and hospitals, researchers here reported.

TORONTO -- Experience in treating tuberculosis, even if it is outside a physician's main area of expertise, appears to play a key role in patient survival, according to researchers here.

SHEFFIELD, England -- Smoking cigarettes seems to be an independent risk factor for HIV infection, according to researchers here. But smoking doesn't appear to be a risk factor in progression to AIDS.

OTTAWA, Ontario -- A large study of women with cosmetic breast implants found they had a suicide rate over two decades that was 73% higher than the general population -- but the rate was similar to that of women who had other cosmetic procedures.

ROCKVILLE, Md. -- Several hospitalizations and one death caused by an outbreak of Escherichia coli 0157:H7 has prompted the FDA to warn consumers to avoid bagged fresh spinach, which the agency said is a possible cause of the outbreak.

ROCKVILLE, Md. -- Several hospitalizations and one death caused by an outbreak of Escherichia coli 0157:H7 has prompted the FDA to warn consumers to avoid bagged fresh spinach, which the agency said is a possible cause of the outbreak.

Two children--one with a history of infection, the other with a history of an allergic reaction--were noted to have postinflammatory hyperpigmentation.

Keratosis Pilaris

A 38-year-old man sought treatment for the intensely pruritic swellings that had arisen on his upper lip 2 weeks earlier (A). These sharply demarcated, tender, boggy, granulomatous, pustular tumefactions are kerions, write Florence Isaac, MD, of Mohammad Dossary Hospital in Saudi Arabia and Shaun Isaac, MD, of St Petersburg, Fla. The diagnosis is based on the history of acute onset, the clinical appearance of the lesions, and the demonstration of a fungus by a potassium hydroxide (KOH) preparation of loose hairs removed from the affected area and by fungal culture. In this case, the KOH preparation revealed fungal filaments, which on culture grew Microsporum canis. A pus swab test should be performed to detect any bacterial copathogen. The differential diagnosis of kerion includes impetigo and carbuncle.