Infectious Disease

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TORONTO -- The bleak early days of the AIDS crisis, when clinicians were grabbing at straws, provided lessons for today, said researchers who reviewed the history of the epidemic -- now in its 25th year -- at the 16th International AIDS Conference here.

NANTES, France --The seventh trial of adjuvant Navelbine (vinorelbine)-Platinol (cisplatin) tips the balance toward improved survival in patients with stage IB to IIIA non-small-cell lung cancer (NSCLC).

TORONTO -- The target of most HIV therapy is the virus itself, but researchers said here that another approach -- blocking cells' entry points and locking the virus out -- is also starting to show promise.

TORONTO -- An investigational pediatric version of a recently approved HIV drug is safe and well-tolerated at two different doses and appears to be effective, researchers said here.

TORONTO -- The transmission of drug-resistant HIV appears to be stabilizing, at least in Europe, but about 9% of newly infected HIV patients still carry a virus that carries resistance mutations to one of the three main classes of anti-retroviral medications.

TORONTO -- HIV patients are 18 times more likely than the general population to become infected with community-acquired methicillin-resistant Staphylococcus aureus (MRSA), and the rate appears to be increasing.

SEATTLE -- For children with acute lymphoblastic leukemia (ALL), the multidrug, multidose regimen of home oral chemotherapy may be too complicated for some parents to master, according to a study here.

TORONTO -- Increased cholesterol and triglycerides in HIV-infected children being treated with highly active antiretroviral therapy (HAART) can be markedly reduced by switching regimens, researchers reported here.

TORONTO -- Even in HIV-infected patients who have tried and failed several drug regimens, the goal should still be to reduce the virus to undetectable levels, according to guidelines presented here.

GENEVA -- The notion of HIV-treatment interruption -- consigned not long ago to the ash heap of failed ideas -- should be revisited, said investigators here.