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Heart disease, stroke, and cancer are leading causes of death in men, but they present to primary care with a variety of other, often difficult-to-diagnose concerns. Take this week’s photo quiz to test your knowledge of men’s health issues.

Swollen Purple Toe

A 20-year-old woman presents in mid-winter with a mildly painful, swollen, and discolored left toe of a week’s duration. What cause do you suspect?

A homeless man with lithophagia; hereditary trichoepithelioma; IBD mimics: can you answer this week's quiz questions about these and 2 other disorders?

Open Leg Wound

This lesion in a previously healthy 40-year-old man, which was initially a small pustule, has enlarged into an open wound. What does this look like to you?

Hairy Hyperpigmented Lesion

A 16-year-old boy had an asymptomatic, hyperpigmented, hairy lesion on his left upper back. What's your diagnosis?

Confusion about multiple insulin products; nonadherence to the prescribed regimen; the patient’s injection technique . . . here: a look at why errors occur when insulin is prescribed-and how to prevent them.

A 45-year-old man of Hispanic ancestry has had mild redness and irritation in both eyes, but he denies any change in vision. What is this?

“My mother was diagnosed with incurable lung cancer. I made a comic strip about it.” The idea: combine the art with the medicine.

The Old Man and AZT

Helios is 80 years old and was given a diagnosis of HIV infection in 1994. He's still taking the same combination of work-horse antiretrovirals he started with. I wanted to talk about changes. Helios didn't.

Women who have post-traumatic stress disorder gain weight more rapidly than women who do not and are more likely to be overweight or obese.