DUARTE, Calif. -- In the face of early-onset breast cancer, too few women in the family can taint the potential accuracy of models to determine the need for full-blown BRCA testing.

INDIANAPOLIS -- Infants and toddlers are the children most likely to be injured in elevator accidents, reported investigators here. Soft-tissue injuries to upper extremities are the most common trauma types.

BARCELONA, Spain -- Ofatumumab (HuMax-CD20), an investigational fully human antibody, appears to be safe and effective for rheumatoid arthritis, researchers said here.

REYKJAVIK, Iceland -- There's more evidence that mutations in the BRCA2 cancer susceptibility gene can contribute to prostate neoplasia as well as to breast and ovarian malignancies.

BARCELONA, Spain -- Rheumatoid arthritis responds more quickly to certolizumab pegol (Cimzia) than to other tumor necrosis factor-a inhibitors, researchers have found.

MINNEAPOLIS, Minn. -- When arthritis patients took extended release morphine sulfate (Avinza) on awakening, they got to sleep more easily at night and slept better and longer, researchers found.

BERKELEY, Calif. -- Arsenic exposure increases the risks of bladder and lung cancer starting a decade after chronic exposure, researchers here reported.

INDIANAPOLIS -- Authorizing emergency department physicians to send ST-elevation myocardial infarction (STEMI) patients directly to the cath lab resulted in 71% being treated within 90 minutes of symptom onset.

PITTSBURGH -- A new mathematical model of sepsis may help physicians make better clinical decisions, researchers here hope.

SANTA MONICA, Calif. -- The higher the number of chronic medical problems patients have, the better the quality of their healthcare tends to be, a finding that should reassure quality-of-care watchdogs.

CHICAGO -- Most intracranial arterial aneurysms in children appear to arise spontaneously in the anterior circulation, and not, as commonly believed, as a result of trauma, infections, or vascular malformations, reported investigators here.

WASHINGTON, D.C. -- The odds of getting an NIH grant are a lot better for Ph.D.s and M.D.s who also hold a Ph.D. than for physicians who have a medical degree alone, one study showed.

CINCINNATI -- For treating the chronic pain and other symptoms of fibromyalgia, the anticonvulsant gabapentin (Neurontin) proved safe and effective, researchers here reported.

VIENNA -- Three drugs, two approved and one in the pipeline, are improving care for patients with severe rheumatoid arthritis (RA), according to clinicians here.

MINNEAPOLIS -- Poor sleepers may be too tired during the day to eat properly, according to researchers here.

CHICAGO -- A child who has a body mass index in the range of the 85th to 95th percentile for age and sex should be considered overweight, not "at risk of overweight".

NEW YORK -- Ovarian cancer is associated with a set of specific symptoms that should trigger further evaluation by a physician, "preferably a gynecologist," according to a consensus statement released today.

PROVIDENCE, R.I. -- Even mild preoperative anemia or polycythemia were associated with an increased risk of death and serious cardiac events in older veterans having major noncardiac surgery, researchers here reported.

IOWA CITY, Iowa -- Black Medicare patients were less likely to receive coronary revascularization for acute MI than white patients, even if the hospital offered those services.

DANBY WISKE, England -- The recurrence of sudden infant death syndrome (SIDS) within families may be less common than reported, according to a literature review.