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Although the incidence of bladder cancer innon-smoking asymptomatic women underage 40 years who have not been exposed toenvironmental/occupational carcinogens isextremely low, current standards still recommendcystoscopy.

Colonoscopy revealed diverticulosis in a 47-year-old man who had presented with rectal bleeding. A polypoid lesion was noted in the sigmoid colon.

A 57-year-old woman presents with swelling of the hands that began several weeks earlier and is now worsening. She denies joint pain, and she has no history of trauma or significant vascular disease. She has had pneumonia several times; each episode was successfully treated with antibiotics. She has smoked 2 packs of cigarettes a day for the past 20 years

The goal of treatment in acute coronary syndromes is the restoration and maintenance of myocardial perfusion. To this end, numerous pharmacological agents are available, as well as percutaneous coronary intervention (PCI).

Urge incontinence, also referred to as overactive bladder (OAB)-wet, is the involuntary loss of urine accompanied by or immediately preceded by a sensation of urgency. It has a reported overall prevalence of 16.0% in men and 16.9% in women. Currently, the mainstay of management for symptomatic urgency and OAB-wet is medical therapy.

During week 28 of her pregnancy, a 28-year-old woman presented with a gingival hemangioma between the right upper central incisor and canine tooth. The asymptomatic lesion arose during the thirteenth week of her pregnancy; it gradually enlarged and bled occasionally with minor trauma.

Drance hemorrhages are disc hemorrhages that lie within the peripapillary retinal nerve fiber layer.

For severe constipation in hospitalized patients who do not have bowel obstruction or stool impaction and who have not responded to routine oral laxatives, suppositories, or sodium phosphate enemas, try a lactulose enema.

It can be difficult to tell whether a vaguely palpable abdominal mass is intra-abdominal, in the abdominal wall, or extra-abdominal. To differentiate among these 3 types, ask the patient, while lying on the examination table, to lift either the head or legs; then palpate the mass again.

NEW ORLEANS -- When patients are being evaluated for antithrombin therapy in association with percutaneous coronary interventions, doctors have multiple choices that make it possible to tailor therapy, said a Cleveland Clinic investigator,

NEW ORLEANS -- Cardiovascular risk is not static and intermediate risk patients may be on their way toward high risk, although that migration might be avoided or slowed by aggressive management.

ROCKVILLE, Md. -- The FDA announced today that Novartis has agreed to withdraw Zelnorm (tegaserod), the only approved drug for irritable bowel syndrome (constipation), after a pooled analysis of 29 placebo-controlled, short-term trials found a small but statistically significant increase in ischemic events, including angina and stroke. The analysis identifed 13 such events, including one death, in more than 11,600 patients treated with tegaserod versus one event among a placebo group.

ROCKVILLE, Md. -- FDA advisers have recommended that the agency approve a therapeutic personalized vaccine for treatment of metastatic prostate cancer that may increase survival by several months.

BALTIMORE -- Some cases of idiopathic pulmonary fibrosis may be the result of genetic flaws rather than autoimmune disease, according to researchers here.

NEW ORLEANS -- Succinobucol (AGI-1067), a novel potent antioxidant for acute coronary syndrome, missed the primary endpoint in a phase III trial, researchers reported here. But it outperformed placebo in secondary endpoints.

ROCKVILLE, Md. -- The FDA today withdrew the Parkinson's drug pergolide -- a dopamine agonist sold as Permax and as a generic -- because of an increased risk of valvular heart disease.

NEW ORLEANS -- Office-based use of the biomarker pro-B-type natriuretic peptide (proBNP) to help diagnose the cause of dyspnea in the general population may be feasible, Danish researchers said here.

SEATTLE -- Three percent of new breast cancer patients also have mammographically occult malignant tumors in the contralateral breast that can be detected only by magnetic resonance imaging, researchers reported.