Prednisone for Stevens-Johnson Syndrome
April 15th 2002Levofloxacin, 500 mg/d, had been prescribed for a 74-year-old woman who had a urinary tract infection. The patient had type 2 diabetes and hypertension. She was allergic to sulfa drugs. Two hours after taking the first oral dose of the antibiotic, painful blisters developed on the lower lip and soft palate.
Chronic Discoid Lupus Erythematosus: Impetigo Mimic
April 2nd 2002Numerous plaques, some with yellow crusting and central scarring, had erupted primarily on the face and neck of a 46-year-old man. A single lesion had developed on his left elbow as well. The lesions were initially diagnosed as impetigo, but they failed to resolve after 2 courses of oral cephalexin.
Jejunal Stenosis: A Capsule Review
April 1st 2002This condition is characterized bya localized narrowing of the jejunumwithout a disruption of continuityor defect in the mesentery. At thestenotic site, there is often a short,narrow segment with a minute lumenwhere the muscularis is irregularand the submucosa is thickened.The resultant intestinal obstructionis incomplete.
Paralytic Ileus: Causes, Diagnosis, Management
April 1st 2002This obstruction is caused by a failure of intestinal peristalsis;there is no evidence of mechanical obstruction.Paralytic ileus is common after abdominal surgery, especiallyif anticholinergic drugs are given preoperativelyand/or narcotics are used postoperatively. It usually lasts2 to 3 days. Paralytic ileus may also be caused by peritonitis;ischemia or surgical manipulation of the bowel; retroperitonealhemorrhage; spinal fracture; systemic sepsis;shock; hypokalemia; uremia; pharmacologic agents (eg,vincristine, loperamide, and calcium channel blockers);diabetic ketoacidosis; and myxedema.
Postseizure Neurogenic Pulmonary Edema
March 1st 2002A 58-year-old man with a history of a seizure disorder was hospitalized with acute-onset shortness of breath immediately following a tonic-clonic seizure. He was afebrile; in respiratory distress; and hypoxic, with an oxygen saturation of 84% on room air. Auscultation revealed bibasilar crackles and an S3 gallop. The patient was given noninvasive mechanical ventilatory support, oxygen, and diuretics.
Photo Clinic: Gastric Duplication
March 1st 2002Alimentary tract duplications are uncommon. Gastric duplication accounts for only 3.8% of these duplications. The cause is not known, but faulty separation of the endoderm and notochord early in embryonal development is thought to be responsible. The anomaly occurs in twice as many female as male infants.
Multimicrobial Skin Infection and Staphylococcal Infection
March 1st 2002Painful erosions developed on the sole of a 14-year-old girl's foot several weeksearlier. Within the last few days, the condition has spread to the other sole.The patient is otherwise healthy and takes no medications. She enjoys playingsoccer and has no history of trauma.
Acute Myelogenous Myelomonocytic Leukemia
February 1st 2002A middle-aged woman had had alow-grade fever, sore throat, and malaisefor 1 week. Her physician prescribedamoxicillin. Three days afterstarting the medication, an asymptomaticerythematous and petechialeruption developed over the patient’sentire body.