Brush up on RSV: Symptoms, Risks, and Treatment
Respiratory syncytial virus is an age-old winter foe that could affect many of your patients this year. Take a minute and scan these facts for a refresher.
Daily Dose: Parent-Pediatrician Vaccine Discussions Lagging?
Your daily dose of clinical news you may have missed.
Parent-Pediatrician Vaccine Discussions are Lagging, National Poll Finds
One in 7 parents have not discussed vaccines with their child's primary clinician during the 2-year pandemic period, according to a CS Mott Children's Hospital poll.
CDC Reports Flu Activity at 10-year High as COVID-19 and RSV Fill Hospital Beds
Overall flu activity is at a 10-year high, according to the CDC's most recent influenza surveillance report, while US hospitals are already overwhelmed.
Large Analysis of Hospitalized Children with Influenza Supports Early Oseltamivir Treatment
Early oseltamivir use reduced the length of hospitalization and risk for hospital readmission in children hospitalized with influenza, according to new research.
Vaccine Confidence Significantly Eroded During Pandemic, Across Demographics
Confidence in vaccines is lower post-pandemic across all demographic groups and is not limited to traditional "anti-vaxxers," say authors of a new study.
Pediatric RSV Vaccines: Why Are We Still Waiting?
I have admitted infants to the hospital every winter for 40 years, yet I still don't have good answers for anxious parents watching their child struggling to breathe.
7 RSV Myths and Facts: Prepare for the New Wave of Misinformation
RSV is back for the 2022-23 respiratory virus season and is unfamiliar to many. Click through this quick collection of myths already in circulation to prepare.
Fluticasone Exhalation Delivery System Reduced Exacerbations, Need for Antibiotics in Patients with Chronic Sinusitis
IDWeek 2022: New data show a greater than 60% reduction in acute exacerbations and need for antibiotics in patients with CS who used fluticasone propionate nasal spray.
The Daily Dose: Adult RSV Vaccine
Your daily dose of clinical news from Patient Care Online.
GSK Announces Positive Pivotal Phase 3 Data for Adult RSV Vaccine Candidate
The investigational respiratory syncytial virus vaccine had an overall efficacy of 82.6% against RSV-LRTD, 94.6% against severe disease, and 94.1% in adults with comorbidities.
Remdesivir for Severe COVID-19: Expert Guidance on Use in Clinical Practice
Elizabeth Sapey, PhD, discusses how the updated treatment recommendations from the World Health Organization may impact future use of remdesivir.
Remdesivir for Treatment of Severe COVID-19: Expert Reviews Latest Evidence
Elizabeth Sapey, PhD, discusses findings from the SOLIDARITY study and similar research on the efficacy of remdesivir for treatment of severe disease.
WHO Recommends Remdesivir for Severe COVID-19: Expert Perspective on Updated Therapeutic Guideline
Elizabeth Sapey, PhD, discusses the updated recommendations and the research that prompted the decision.
Antivirals Recommended for Influenza Treatment & Chemoprophylaxis: Basics, Notes, Cautions
This influenza antiviral brush-up slide show reminds you of key features of the 4 FDA-recommended medications, at-a-glance.
WHO Guideline Update Recommends Against 2 COVID-19 Monoclonal Treatments
WHO: Evidence is lacking for clinical effectiveness of Xevudy and Regen-Cov against the COVID-19 variants that are currently circulating.
Phase 3 Trial Now Underway of Investigational mRNA-based Influenza Vaccine
Pfizer announced that the first participants have been dosed in a novel phase 3 efficacy clinical trial of its quadrivalent modified RNA influenza vaccine candidate.
Study: At-home COVID-19 Tests Less Effective After Omicron Emergence
The performance of 3 commercially available COVID-19 home-testing kits worsened during the emergence of the omicron variant, according to a new cross-sectional study.
COVID-19 Bivalent Booster Shot Q&A for Clinicians
Get answers to 7 questions you may have regarding bivalent booster dose vaccination for patients from the US Centers for Disease Control and Prevention.
The Future of US Antimicrobial Resistance is in Our Hands and There is Work to Do
Steer clear of antibiotic Rxs whenever possible, says Anne Meneghetti, MD, to help the US get back to pre-COVID levels of antimicrobial stewardship.
Primary Care Can Help Restore US Antibiotic Stewardship, Starting with Flu Shots
Preventing viral infections with vaccination can keep the most vulnerable out of the hospital, reducing the risk of bacterial superinfections.
Superinfection Rate in Hospitalized COVID-19 Patients was Found to be Low
Only 9% of inpatients with COVID-19 had a bacterial superinfection that could be treated with antibiotics which curbed use of broad-spectrum antimicrobials.
Pfizer Reports Positive Topline Phase 3 Data for Bivalent RSV Vaccine in Older Adults
Pfizer announced that a single dose of the vaccine, RSVpreF, demonstrated 85.7% efficacy against severe disease, defined by ≥3 symptoms.
Antimicrobial Resistance During COVID-19 Gained New Ground: Expert Perspective
Widespread antibiotic prescribing in the first year of the pandemic set back US progress on the fight against antimicrobial resistance, says Anne Meneghetti, MD.
New Real-world Study Finds Average Length of COVID-19 Infectiousness is 5 Days
A new real-world study found that two-thirds of patients with COVID-19 were still infectious 5 days and one-fourth at 7 days after symptom onset.
FDA: Repeat At-home COVID-19 Antigen Tests to Reduce Risk of False Negative Result
The FDA now recommends serial testing following a negative result on any at-home COVID-19 antigen test to reduce the risk of a false negative result.
New CDC COVID-19 Guidelines Reduce Quarantine Requirement after Exposure
After exposure to COVID-19, asymptomatic individuals in low-risk settings no longer need to quarantine, says the CDC; masking is still recommended.
5 Clinical Updates in Tick-borne Disease Research
Lyme disease vaccine being tested in phase 3 trial, Lyme disease diagnoses up 357%, and 3 more updates on tick-borne diseases.
FDA EUA for Monkeypox Virus Vaccine Expands Available Doses by 5-Fold
A smaller dose given by intradermal injection will expand the total US supply by a factor of 5, FDA says.
Monkeypox Declared US Public Health Emergency by HHS
Monkeypox will now be treated as a public health emergency in the US where the outbreak has become the largest in the world, according to authorities.