Screening

Xavier Llor, MD, of Yale Medicine, discusses what the updated guidance from the American Cancer Society on colorectal cancer screening mean for primary care.

ACS updated colorectal cancer screening guidance, reaffirming screening at age 45 and adding newer stool-based and blood-based options.

ACOG 2026: James A. Simon, MD, discusses off-label evidence for elinzanetant in breast cancer survivors on anti-estrogenic therapy.

ACP Internal Medicine Meeting 2026 highlights: new mammography guidelines, AI scribe limitations, and muscle loss risks with GLP-1 weight loss drugs.

ACP guidance recommends biennial mammography for women aged 50-74 and shared decision-making for screening in women aged 40-49.

Episode highlights include a new AD blood test for PCPs, sleep effects of elinzanetant among postmenopausal women, lung cancer screening gains, and more.

In 142 000 adults, adding Galleri to standard screening reduced stage IV diagnoses over time in a prespecified group of 12 cancers, according to new data.

Physician researcher Fendrick offers an expert perspective on why removing cost barriers matters, and why navigation and patient realities still determine whether CRC screening succeeds.

GRAIL advances cancer detection with FDA application for Galleri, a groundbreaking blood test aimed at early detection of multiple cancers.

Colorectal cancer emerges as the top cancer killer for US adults under 50, highlighting urgent needs for early detection and screening strategies.

This episode reviews intranasal epinephrine use, pediatric atopic dermatitis data, dementia screening tools, adolescent TMS, and oral PCSK9 therapy.

Your daily dose of the clinical news you may have missed.

Psychiatrist Gus Alva, MD, discusses newer, faster depression screening approaches that primary care clinicians can implement.

Fendrick discusses the balance between colonoscopy and non-invasive tests for colorectal cancer screening, aiming for better patient outcomes.

Completion of the screening pathway—not test selection alone—may define quality going forward.

Moving patients from considering screening to completing it remains the central challenge in colorectal cancer prevention, Fendrick explained to Patient Care.

Your daily dose of the clinical news you may have missed.

A cohort study of 531 851 primary care patients found routine AUDIT-C alcohol screening scores predict 8-year all-cause mortality, with strongest effects in younger adults.

Your daily dose of the clinical news you may have missed.

The updated guideline from the American Cancer Society introduces self-collection for HPV testing and new exit criteria to enhance accessibility.

Two new Cochrane reviews confirm HPV vaccines significantly reduce cervical cancer risk, especially when given before age 16, with no serious safety concerns.

Universal age-based screening, starting at age 40, could detect more than 90% of tumors compared to risk-based screening, according to Feinberg School of Medicine researchers.

Real-world data from 20 000 patients demonstrate significantly higher adherence rates with Shield blood test vs colonoscopy and stool-based screening methods.

Donna Plecha, MD, discusses how AI-powered mammography risk prediction and polygenic risk scores will enable personalized breast cancer screening within the next decade.

Breast imaging expert, Donna Plecha, MD, provides a roadmap for primary care physicians to implement risk assessment tools and high-risk clinic referrals in their practice.