Neurology

For each cardiometabolic disease, the risk of all-cause dementia rose by 42%; the risk rose 26% for Alzheimer disease and 64% for vascular dementia. Temporal onset and genetics play key roles.

Approval of lecanemab under FDA's accelerated pathway requires the company to provide phase 4 study evidence to confirm the agent's clinical effect.

Patient Care Guideline Toplines summarize newly revised and updated clinical recommendations from professional societies for convenient, at-a-glance review.

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Variable BMI patterns across the lifespan may be a prodromal marker of dementia; a pattern of midlife increase followed by decrease was associated with greatest risk.

Having both conditions while pregnant in the current study conferred more than double the risk of future CVD vs having either condition alone.

New Data Shows REST-LGS Screening Tool Identified Over Half of Adults with Drug-Resistant Epilepsy in Residential Care Setting Likely to Have LGS

From crime rates and credit scores to average health and hours worked in a week, find the 5 states that rank highest and the 5 lowest across 9 composite measures of stress.

The NIH has awarded $11 million for evaluation of a 5-minute, largely visual screening test for dementia intended for use in primary care practice.

Similar reduction in risk was reported for both lobar and nonlobar intracranial hemorrhage with longer statin treatment associated with greater protection, according to Danish investigators.

Approved in 2020 as Nexletol, bempedoic acid as the first ATP citrate lyase inhibitor and oral non-statin therapy to meet the MACE-4 primary endpoint.

Being most physically active in the late morning had a 16% decreased risk of coronary artery disease and a 17% decreased risk of stroke compared to midday.

Pandemic-related stress and depression may be slowing recovery from long COVID-19 and other illnesses, according to researchers.

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"Cardiac rehabilitation is for life," says the NYU Langone Rusk Rehabilitation medical director of cardiac/pulmonary rehab, and he advocates empathy and compassionate understanding.

New findings suggest that the elevated risk of overdose with benzodiazepine use for sleep disorders is a critical safety consideration when treating young people.

Large study comparing spinal cord stimulators to conventional medical management found a lack of clinical benefit for most patients and possible harm to some.

A daily step count of as few as 3800 was associated with a 25% reduced risk of incident dementia in a cohort of 78 000 adults; the optimal count was fewer than 10 000.

Study participants who had HZ were at 30% greater sustained risk of stroke and CHD vs those who had not had HZ in this large multicohort prospective study.

While 60% of US psychologists have no openings for new patients, demand for treatment continues to rise, especially among adolescents and health care workers.

The man, in his 30s, has seen 2 specialists, received 2 diagnoses, and is now in the ED for persistent pain that is worsened by eye motion. Can you dx?

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Study authors saw a positive dose-response relationship driven by hemorrhagic stroke in young adults who were moderate-to-heavy drinkers in their 20s and 30s.

The Nerivio REM device demonstrated a statistically significant reduction in migraine days/month vs a placebo device in both chronic and episodic migraine.

Apixaban was associated with up to a 28% lower risk of GI bleeding vs the 3 other direct oral anticoagulants in the first large-scale comparative analysis.