Seizures are among the most common neurologic conditionsencountered in the primary care setting. However, they havereceived scant attention in standard textbooks and in themedical literature generally-perhaps because the topic cutsacross so many specialties. Here, an international team ofexperts fills this void with a comprehensive discussion of thecauses and management of seizures associated with a widevariety of medical problems-including organ failure,organ transplantation, electrolyte imbalance, endocrine disorders,cardiorespiratory disorders, cancer, fever and systemicinfection, medication, alcohol, illicit drug use, andenvironmental toxins. Chapters cover the various types ofseizures and their pathophysiology, how to distinguishseizure from syncope, seizures in the ICU, and the use ofanticonvulsants.

You routinely order laboratory screeningpanels, including serum liver enzymemeasurements, for nearly everypatient who has a complete physicalexamination or who is seen for any ofa host of other complaints. If you findabnormal liver enzyme levels, your familiaritywith the common causes andthe settings in which they occur mayenable you to avoid costly diagnosticstudies or biopsy.

A 26-year-old woman complained of flatus and fecal incontinence of solid stool.One year earlier, she was delivered of a 3.86-kg (8.5-lb) infant; a severe perinealtear was repaired after the birth.

Many patients who experience anepisode of severe low back pain willhave a recurrence at some time in theirlife. Therefore, it is usually prudent toprescribe a long-term exercise programto minimize the pain and frequency ofrecurrences. Such a program should include3 types of activities:

Low back pain affects up to 80% ofAmericans at some point in their lives.1This common ailment can be mentallyand physically debilitating.

Q:What is the best and most efficient method ofevaluating pulmonary function in primary careoffice practice?

Liperoti R, Pedone C, Lapane KL, et al, UniversitaCattolica del Sacro Cuore, Rome,and other centers. Venous thromboembolismamong elderly patients treated withatypical and conventional antipsychoticagents. Arch Intern Med. Dec 12/26, 2005;165:2677-2682.

Outbreaks of Legionnaires diseasehave been traced to the inhalationof aerosolized water containing Legionellapneumophila, often originatingfrom cooling towers. A recentstudy of an outbreak in Franceindicates that the distance of airbornetransmission of L pneumophilamay be greater than previouslythought.

Abstract: Smoking cessation is still the most important intervention in patients with chronic obstructive pulmonary disease (COPD), regardless of sex. There is some evidence that nicotine replacement therapy may be less effective in women than in men. However, women may derive greater benefits from a sustained quit attempt. For example, one study found that compared with men, women who were sustained quitters had a greater initial rise and a slower age-related decline in forced expiratory volume in 1 second. Men and women do not appear to differ in their response to bupropion or to the various types of bronchodilators. A number of factors contribute to the increased risk of osteoporosis in women with COPD. Both smoking and the degree of airflow obstruction have been identified as important risk factors for osteoporosis. Women may be particularly susceptible to the effects of smoking on bone metabolism. Immobility and decreased physical activity have also been shown to accelerate bone loss. (J Respir Dis. 2006;27(3):115-122)

A 37-year-old man presented withnew-onset fever and abdominal painof several days’ duration. No respiratorysymptoms were reported.The patient had a history of multiplestab wounds to the abdomenand back, resulting in chronic backpain and a neurogenic bladder.During a previous hospital admission,he was treated for Enterobacterpyelonephritis with intravenousgentamicin for 12 days.

Chronic headache that worsened when she bent forward and episodes of usually unilateral vision loss sent a 34-year-old woman for medical consultation. The vision loss occasionally occurred in both eyes simultaneously.

Are follow-up radiographs or laboratory studies needed when lentigo maligna has been completely excised and a biopsy has been performed?

Excess weight increases the risk of having a heart attack, stroke, high blood pressure, arthritis, diabetes, depression, fatigue, and certain types of cancer. Losing weight and keeping it off are very difficult for most persons who are overweight. Here are some suggestions to help you lose pounds and keep your weight down.

In this article, we review the factors that contribute to obesity. We then describe effective approaches to weight control, including exercise, dietary modification, drug treatment, and bariatric surgery.

Phenytoin is one of the most commonly prescribed antiepileptic drugs in both acute and chronic settings; its use has been extensively described. Nevertheless, interactions between phenytoin and numerous other drugs continue to complicate seizure therapy; these have been documented in case reports, studies, textbooks, and epilepsy reviews.

A 39-year-old woman who had a fever and episodes of nonbloody vomiting for 5 days presented to the emergency department after the sudden onset of severe, left-sided flank pain (10/10 severity) that was sharp, constant, and radiated to the front. She had no associated urinary symptoms, vaginal discharge, or bowel disturbances. Her last menses, 10 days earlier, was regular. Aside from a urinary tract infection 2 years earlier, her medical history was insignificant.

A 56-year-old man presents with diffuse erythema. He has not changed his routine or eaten anything unusual. The rash initially appeared the previous night as asymptomatic erythema on the face and body. On awakening in the morning, the patient noticed that the erythema had spread over most of his body and had become pruritic. Over-the-counter diphenhydramine did not relieve the symptoms.

To easily drain an ulnar bursa or a patellar effusion of any size--and simplify preparation of the aspirate for transfer--use an evacuated blood draw kit with an 18-gauge needle attachment, a see-through-labeled tube coated with whatever anticoagulant your laboratory specifies, and several large additive-free tubes. Begin with the coated tube

When examining a patient who complains of earache, start by looking in the "good" ear.

Dermclinic: A Photo Quiz to Hone Dermatologic Skills