Infectious Disease

Latest News


CME Content


A 56-year-old man presents with diffuse erythema. He has not changed his routine or eaten anything unusual. The rash initially appeared the previous night as asymptomatic erythema on the face and body. On awakening in the morning, the patient noticed that the erythema had spread over most of his body and had become pruritic. Over-the-counter diphenhydramine did not relieve the symptoms.

During a basketball game, a 23-year-old soldier had been hit in the right eye with the ball. The eye was slightly red with copious lacrimation; vision was normal. Using a Wood lamp and fluorescein dye, MAJ Kenneth S. Brooks, APA-C, of Camp As Sayliyah, Doha, Qatar, examined the patient's eye for corneal abrasions and saw these results. Note the almost complete halo of dye, with gaps at the 6 o'clock and 11 o'clock positions on the iris. This curious phenomenon was baffling until the soldier was asked about recent eye surgeries; he answered that he had undergone photorefractive keratectomy (PRK) several months earlier.

Monday morning your nurse hands you charts for 4 new patients. Each patient is a woman with widespread body pain, stiffness, and fatigue. All have already been evaluated by another physician and were advised that they should reduce stress and practice distraction techniques. They are in your office today seeking a second opinion.

A 45-year-old man comes to see you for a routine physical.He has no complaints and no significant medical history.However, while questioning him you discover that he usedintravenous heroin until about 10 years ago-and sometimesshared needles. He also drank 6 or more beers a day for about 20 years, a practicehe stopped at the same time that he quit using illicit drugs. He has multiple tattoos,which were done at commercial parlors. He is married but has no children. His wife hasno history of hepatitis. Physical examination is unremarkable.

A nonhealing ulcer recently developedin a painful facial rash that hadworsened over several months. The44-year-old patient is a heavy drinkerwith a history of elevated liver functionlevels. She has had numerousunprotected sexual contacts over theyears.

Abstract: In the assessment of community-acquired pneumonia, an effort should be made to identify the causal pathogen, since this may permit more focused treatment. However, diagnostic testing should not delay appropriate empiric therapy. The selection of empiric therapy can be guided by a patient stratification system that is based on the severity of illness and underlying risk factors for specific pathogens. For example, outpatients who do not have underlying cardiopulmonary disease or other risk factors can be given azithromycin, clarithromycin, or doxycycline. Higher-risk outpatients should be given a ß-lactam antibiotic plus azithromycin, clarithromycin, or doxycycline, or monotherapy with a fluoroquinolone. If the patient fails to respond to therapy, it may be necessary to do bronchoscopy; CT of the chest; or serologic testing for Legionella species, Mycoplasma pneumoniae, viruses, or other pathogens. (J Respir Dis. 2006;27(2):54-67)

Most primary care practitioners approach the patient who complains of dizziness with some trepidation. This is chiefly because the differential diagnosis involves multiple organ systems and a wide variety of disorders. In this article, I offer a rational, straightforward, and cost-effective approach that uses only minimal, selective diagnostic testing.

Ringworm

A 5-year-old boy, who lives on a farm and routinely plays with his pet dogs, presented with these scaly, inflamed macules with a central clearingon the abdomen and forehead.

My patient has been hospitalized for pneumonia several times by different physicians. He has never received the pneumococcal vaccine. Can this vaccine begiven during the patient’s hospital stay?

A 51-year-old man who has been hospitalized for 7 days for acute pancreatitis has a predischarge platelet count of 812,000/µL.

There's a curse frequently attributed to the Chinese, "May you live in interesting times." It seems that we find ourselves living in interesting times right now. The Department of Homeland Security recently heightened our threat levelfrom code yellow to code orange. Duct tape, plastic wrap, and flashlights are in short supply at local hardware stores. There’s been more talk about smallpox and the smallpox vaccine, and parents and colleagues are eager for more information.

THE CASE

A 7-year-old girl isbrought to your office by her parents,who state that she has had rednessaround her left eye for the past 2 to 3days. During the last 24 hours, therehas been a marked increase in rednessand soft tissue swelling that hasimpeded the child’s vision. There isno history of trauma or eye infection.

Until recently, the specter of biologicwarfare or bioterrorism was infrequentlydiscussed by most physicians,despite the attention it had receivedfrom novelists, screenplay writers,politicians, and military defense strategists.Thankfully, most physicians havestill never encountered the malevolentuse of biologic agents, nor have theytreated a victim of a biologic attack. Infact, despite their occasional occurrencein a “natural setting,” as well asin recent events, clinical cases involvingany of the classic biothreat agentsare rarely encountered even by mostinfectious disease physicians.

Most pain in or around the oral cavity is attributable to tooth or mucosal pathology. However, tooth or mucosal pain may also be caused by a variety of other conditions, including brain pathology; vascular inflammatory and cardiac disease; jaw infection or neoplasm; neuropathic abnormality not associated with central pathology; pathology in the neck and thoracic region; myofascial and temporomandibular joint pathology; and disease of the ear, eye, or nose, or of the paranasal sinuses, lymph nodes, and salivary glands. Accurate diagnosis is facilitated when the features of pain presentation in this region are understood.