Infectious Disease

Latest News


CME Content


In patients with underlying disease, a preoperative evaluation and targeted perioperative management strategies can minimize surgical complications and maximize healing. This article focuses on how to identify surgery patients at risk for complications caused by diabetes, chronic obstructive pulmonary disease (COPD), and other medical conditions; I also describe strategies to minimize such risk.

Rectovaginal Fistula

Following a complicated vaginal delivery 4 months earlier, a 22-year-old mother of a healthy 9.5-lb infant girl experienced stool incontinence and leakage. An infection had occurred at the site of the episiotomy shortly after the delivery; fecal and flatus incontinence developed about 2 weeks later.

For 3 days, a 10-year-old girl had redness and vesicles on her right volar wrist. She had not had any pain, fever, or other systemic symptoms.

Asthma is one of the most common chronic diseases worldwide, and its prevalence--particularly among children--is increasing in many countries.1,2 In 1997, an estimated 9.6% of persons in the United States had asthma (Table 1).3

A 10-year-old girl has had a worsening rash for 1 week. The mildly pruritic, nontender eruption initially appeared on the child's thighs and then spread to the arms and face. The child's right hand, feet, and ankles have been swollen for the past 4 days, which has made ambulation intermittently painful.

Gastric Hematoma

The patient is a 12-year-old Hispanic boy with hemophilia A (factor VIII deficiency) and high Bethesda unit factor VIII inhibitor who presented to a clinic after 4 days of abdominal pain and clear, nonbilious vomiting. Viral gastroenteritis had been diagnosed, and the boy was given rabeprazole and promethazine, which failed to resolve symptoms. The patient was hospitalized when he became unable to tolerate oral fluids; his urinary output decreased. He denied fever, diarrhea, hematemesis, hematochezia, and melena.

An enlarging mass was noted on the dorsum of the right fifth toe of a 2-month-old boy during a well-child examination. The firm, immobile mass measured approximately 1 cm in diameter. A congenital abnormality was suspected; the patient was referred to a plastic surgeon for consultation.

Fifth Disease

The parents of a 2-year-old sought treatment for a rash on their son's face. The child had had a low-grade fever for 3 days before the rash erupted. An intermittent lace-like rash was beginning to develop on the extremities. The patient was otherwise asymptomatic.

Identical circular, chocolate-colored spots developed on a 4-year-old boy's palms 2 weeks ago, according to the child's mother. The sharply demarcated, macular lesions were asymptomatic.

Pain and pruritus of the neck and upper chest began to bother a 43-year-old woman several hours after she put on a new copper necklace. Vigorous scratching of the affected area caused excoriation of the skin, which can mask the eruption and complicate diagnosis.

Following mechanical bowel preparation and prophylactic antibiotic therapy, a 59-year-old man underwent transanal excision of a villous adenoma of the distal rectum. Two weeks after discharge, he returned with a temperature of 38.9°C (102°F), abdominal pain, and diarrhea.

Ingrown Toenail

A 15-year-old experienced pain in her toe, particularly when pressure was applied to the foot. An ingrown toenail was the cause of her discomfort.

A 39-year-old man with HIV infection was being treated with antiretroviral therapy. He now sought help for multiple 2- to 3-cm violaceous papules on his right hip and the right lower abdominal area. A biopsy specimen showed intense, atypical lymphocytoid and monocytoid cells with prominent nucleoli, hyperchromatism, and bruised nuclei.

A febrile 65-year-old woman who had suffered a new-onset seizure was brought to the emergency department. The patient-a cigarette smoker-was not coughing and had neither chest pain nor a significant medical history. Her temperature was 39.4°C (103°F). She had nuchal rigidity and Kernig's and Brudzinski's signs of meningeal irritation. Lung auscultation revealed signs of right middle lung consolidation. Her white blood cell count was 1,200/µL. A chest film, seen here, showed a masslike density in the right midlung.

A 72-year-old morbidly obese man who had diabetes mellitus was admitted to the hospital from a nursing home with a fever of 4 days' duration. A tracheostomy had been performed 3 months earlier for respiratory failure. The patient was being treated with corticosteroids for chronic obstructive pulmonary disease.

The foot of a 10-year-old boy demonstrates the unique wandering cutaneous lesions of creeping eruption, or cutaneous larva migrans. This disorder is caused by skin penetration of hookworm larvae. It is seen in the southeastern United States and tropical and subtropical regions throughout the world.

Encountered rarely these days, scarlet fever is believed to be caused by sensitization to an erythrogenic toxin produced by strains of group A β-hemolytic streptococci. Thus, previous exposure to the toxin is necessary for development of the rash seen here-fine, sandpaper-like, and papular on an erythematous background. It usually begins on the trunk and spreads over the entire body within hours or days. Scarlet fever is unusual in infancy, possibly because of maternal transfer of antibodies.