August 1st 2025
Your daily dose of the clinical news you may have missed.
Congenital Nevomelanocytic Nevus
May 2nd 2008This darkly pigmented lesion on the left arm of a 27-year-old man had been present since birth and had slowly enlarged over the past 2 months. Two days earlier, another physician had diagnosed a wart and treated the lesion with liquid nitrogen, which caused erythema of the surrounding skin.
Differentiating the Types of Tinea
May 1st 2008Tinea is caused by dermatophytes that can infect the stratum corneum epidermidis, hair, and nails. Dermatophytosis is a common infection worldwide, and about 20% of the US population is infected.1 Although numerous fungi can cause tinea, Trichophyton, Microsporum, and Epidermophyton are the genera that cause most cases of tinea.2 Classified by the part of the anatomy that is infected, tinea is referred to as tinea pedis, tinea manuum, tinea cruris, tinea corporis, tinea capitis, tinea faciei, tinea barbae, and tinea unguium.
Asteatotic Eczema on Legs and Steroid Rosacea on Face
April 16th 2008For several years, a 71-year-old man has had a mildly pruritic rash on his legs that develops every winter and resolves when the weather becomes warmer. He is scheduled to undergo knee surgery, but the surgeon refuses to perform the operation until the rash has cleared.
Second-Degree Burn From Iontophoresis
April 16th 2008Half way through a 15-minute iontophoresis treatment for de Quervain tenosynovitis of the right wrist, a 42-year-old woman felt exquisite pain but completed the session. After the therapist returned to the room and removed the electrodes, a light gray circular mark about 5 mm in diameter was noted on the skin. The epidermis was gone, and the underlying dermis was also injured. Within 6 hours, a tender, dark red-brown lesion developed.
Silver Nitrate Staining of Fingernails
April 2nd 2008Black discoloration appeared on the fingernails of a 51-year-old white man who had sustained burns on 15% of his body in a house fire 2 months earlier. The discoloration is a typical side effect of silver nitrate, which was applied to his skin and fingernails during the month he was hospitalized. This topical broad-spectrum bacteriostatic agent is used to reduce the risk of infection and mortality in burn patients.
Melanoma Within a Congenital Nevus
January 1st 2008A 48-year-old Hispanic man had a tender, bleeding growth within a darkly pigmented plaque on the right flank. The pigmented lesion had been present since birth; it was previously asymptomatic. The tumor arose out of the mainly flat patch 6 months earlier and had slowly enlarged. The patient worked indoors, wore sunscreen daily, and generally avoided outdoor activities. He had no family history of skin cancer.
Middle-Aged Man with Polyuria and Penile Swelling and Pain
November 1st 2007For 2 weeks, a previously healthy 40-year-old man has had excessive thirst and increased frequency of urination. He awakens at least 5 times every night to urinate. He reports no nausea, vomiting, change in bowel habits, chest pain, or dyspnea.
What Cause of Cold and Flushing in a Basketball Player?
November 1st 2007A 20-year-old white male collegiate basketball player has a 3-year history of marked facial and upper extremity flushing that occurs after about 20 minutes of indoor practice. The flushing is preceded by an intense sensation of coldness, and despite the very noticeable flushing, the involved areas are cold to the touch for some time.
Pyoderma Gangrenosum on Both Legs of a 62-Year-Old Woman
November 1st 2007Worsening painful ulcers on both legs prompted a 62-year-old woman to seek medical attention. She had a history of rheumatoid arthritis (RA), demonstrated by the markedly deformed interphalangeal joints in her thumbs (A), and scleroderma-polymyositis overlap syndrome.
Secondary Syphilis and HIV Positivity
November 1st 2007Six months after testing positive for HIV in 10 bands, a 24-year-old homosexual man presented with a macular rash on his palms and soles. He first noticed the lesions 2 weeks earlier; they were not pruritic or painful. He also had a brighter, more inflamed rash in the groin and antecubital fossae that was presumed to be a yeast infection and was treated with fluconazole. He had no other symptoms.