Neurology

Researchers have devoted themselves to devising ways of blocking the production or accumulation of beta-amyloid. Now scientists are studying other protein targets, including tau.

Most doctors are burned out, overworked, or exhausted. Physicians rarely ask for help.

Mucormycosis, an angioinvasive yeast infection of the Mucorales order of the class of Zygomycetes, often grows in patients with diabetes mellitus, especially in the presence of diabetic ketoacidosis.

Test your clinical skills in this week’s 5-question quiz.

Preseptal cellulitis, myasthenia gravis, squamous cell carcinoma, atheromatous embolism, calciphylaxis are shown here.

My first patient had so many things wrong; he left before I could examine his heart and lungs, ask about chest pain, or reconcile his medication list. After his visit, veteran clinic staff noted they hadn’t seen Jim for years and were surprised he had come in at all. I felt the totality of my medical education had been squandered. They kindly reminded me it had just begun.

A 9-kg 15-month-old girl with new-onset generalized tonic-clonic seizure was discharged with instructions to take carbamazepine suspension (45 mg PO BID [10 mg/kg/d]), which she'd been receiving in the hospital. In the clinic, her carbamazepine blood level was subtherapeutic. The dose was increased to 68 mg PO BID. A week later, the carbamazepine level was still subtherapeutic, but no doses had been missed. What’s the problem here?

If drugs could be developed to target tau, they might prevent much of the neurodegeneration that characterizes Alzheimer disease and help prevent or delay dementia.

Most patients have a sophisticated idea of what causes their headaches, but the chances of this information being wrong are higher than desirable unless the patient formally experimented with triggers.

Heart disease and stroke risk prediction tools may be more useful in predicting cognitive decline in middle-aged patients than a dementia risk test, according to a new study.

Persons who eat a high-fiber diet experience a lower risk of first-time stroke, according to a new meta-analysis that supports current guidelines to increase fiber consumption.

Adding informal, unpaid care to the equation as much as doubled the estimated total national costs.

With no drugs to offer a cure for multiple sclerosis, clinicians should have a wide variety of treatment options available for their patients.

Leukemia, brain tumors (glioma, medulloblastoma), and neuroblastoma constitute the most common types of childhood cancers.

The reduction in dementia is not simply the result of the drugs reducing their blood pressure.

This condition is a more important risk factor than previously thought and should not be taken lightly.

Does this look like melanoma? Which is not true of Löfgren syndrome? Yoga and Afib; what cause of mental confusion? Skin lesions and HIV.. . . See if you can answer this week's quiz questions.

Löfgren syndrome is a form of acute sarcoidosis characterized by a triad of symptoms: hilar adenopathy, erythema nodosum, and arthralgias.

Stroke survival and thoughts of suicide; PCP shortage; pediatric headache treatments; antidepressants and prolonged QT interval; calcium supplements, men, and CVD.

Topiramate and trazadone showed only limited efficacy in pediatric headache. For flunarizine, pizotifen, propranolol, and valproate, no evidence was found to support their use.

Suicidal ideation among stroke survivors (7.8%) was higher than among those with a history of MI (6.2%), diabetes (5.2%), and cancer (4.1%).

Nervous system disorders are common, but the symptoms often resemble those of other medical conditions, complicating the diagnosis.

Neurologic complications associated with Down syndrome include dystonia, epilepsy, psychiatric problems, cardiac defects, and auditory and visual defects.

Stigma correlated most strongly with inability to work and was greater for chronic migraine than for epilepsy or episodic migraine.

The primary goal of treatment is to minimize the progression of foot deformity by achieving and maintaining structural stability of the foot and ankle.