July 24th 2025
The nonsteroidal topical pan-JAK inhibitor provides a potent treatment option for adults with CHE who have not responded to corticosteroids or cannot tolerate them.
Psoriasis in a 13-Year-Old Boy
April 15th 2005A 13-year-old boy presented with an explosive eruption of numerous, small, round, erythematous, itchy plaques on his lower back and lower limbs of 2 weeks' duration. Some of the lesions were scaly. His nails were normal. There was no evidence of arthritis or joint deformity. He had a sore throat a month before the onset of the rash but did not seek medical attention. He was not taking any medication and had no history of joint pain or family history of skin problems.
Rosacea and Polymorphous Light Eruption in a Young Woman
April 15th 2005Is this acneform eruption on a middle-aged woman’s face perioraldermatitis? Rosacea? Pyoderma faciale? Is this pruritic rash related to ayoung woman’s tanning salon visits? Scrutinize the photos, make yourdecisions, and compare your answers with an expert’s.
Hidradenitis Suppurativa and Cystic Acne
March 1st 2005Painful cysts on the sternal and left axillary regions that had worsened over the past 3 weeks prompted a 42-year-old man to seek medical care. He reported that similar lesions in the same distribution first arose when he was 25 years old, and they recur each year. He denied having cystic acne in adolescence.
Nummular Eczema: Don't Mistake it for a Fungal Infection
February 1st 2005The multiple, uniformly scaly, coin-shaped, papulosquamous lesions shown here on the lower leg of a 61-year-old man had persisted for 3 months despite application of topical clotrimazole and 1% hydrocortisone. The rash involved only the legs and was variably pruritic. The patient had a long history of dry skin.
Oral Herpesvirus Infection With Impetigo Bullosa
February 1st 2005For 3 days, a 5-month-old infant had a red, papular, nonpruritic rash around her mouth and vesicles on her hands. The child was being breast-fed by her mother, who had a similar rash around her nipple. The child was afebrile, and the physical examination revealed no abnormal findings. There was no history of allergy or change in diet.
Discoid Lupus Erythematosus in a 46-Year-Old Man
November 1st 2004A 46-year-old man complained of “irritation” in the groin of several months’ duration. Ted Rosen, MD, of Houston noted a tender, macerated, hypopigmented plaque at the junction of the scrotum and upper inner thigh. At the periphery of the lesion was some detectable erythema and within the plaque were several small, superficial erosions.
Cutaneous and Pulmonary Coccidioidomycosis
September 1st 200435-year-old Hispanic man presented with nonproductive cough; dyspnea; fever; and a painful, ulcerated, 1.5-cm, red-brown plaque on the left flank. He had had the lesion for 3 months and the symptoms for 1 week. The patient had grown up in Arizona, and he traveled there 4 months before the lesion arose.